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LMU 78 – The Mighty Mineral: Magnesium’s Impact on Blood Pressure

LMU-78

LMU 78 – The Mighty Mineral: Magnesium's Impact on Blood Pressure

Source: American Journal of Clinical Nutrition (September 2017)

Lifestyle Medicine Update (January 19, 2017)

Introduction

In the intricate tapestry of human health, the quest for solutions to prevailing health issues often takes researchers on a journey of exploration. In September 2017, the American Journal of Clinical Nutrition bore witness to a study that ventured into the realm of magnesium supplementation. This study, resplendent in its pursuit of understanding, delved into the impact of magnesium on blood pressure levels among individuals with prediabetes, insulin resistance, or noncommunicable chronic diseases. This endeavor sought to unravel the connection between magnesium supplementation and blood pressure reduction, casting light on a vital aspect of human well-being.

Unravelling the Study: Magnesium’s Role in Blood Pressure Regulation

Guided by the spirit of scientific inquiry, the study unfurled its methodology. The focus rested on individuals harboring prediabetic conditions, insulin resistance, or chronic noncommunicable diseases. A mosaic of eleven randomized controlled trials emerged as the foundation for this exploration. These trials wove a narrative that encapsulated magnesium supplementation’s potential to curtail high blood pressure in individuals bearing this unique profile.

As the pieces of evidence coalesced, the study laid bare its findings. Among the eleven trials, a total of 543 subjects with varying follow-up periods, spanning from 1 to 6 months, formed the canvas. Within this intricate tableau, the dosage of magnesium supplementation oscillated between 365 to 450 mg/d. Baseline and trial-end blood pressure readings etched a comprehensive picture of magnesium’s impact.

Magnesium’s Silent Symphony: Unveiling the Findings

The culmination of these trials yielded a symphony of findings, resonating with profound implications. An orchestration of evidence revealed a noteworthy reduction in systolic blood pressure – a resounding decrease of over 4 mmHg (4.18 mm Hg). The diastolic counterpart, too, yielded to magnesium’s influence, witnessing a reduction of over 2 mmHg (2.27 mm Hg). Within these figures lay a testament to magnesium’s potential as a guardian against high blood pressure.

Reflections on the Study: Bridging Science and Lifestyle

Interpreting the study’s findings is akin to viewing a vibrant tapestry of health. This revelatory journey offers insights that ripple across the realm of well-being. The bridge between scientific revelation and practical application becomes apparent, invoking reflection on the avenues available for blood pressure management.

    • The Weight of Health: A cornerstone of blood pressure management resides in shedding excess weight. A weight reduction of 10-15% can wield transformative effects, rendering this journey a powerful ally against high blood pressure.
    • Harmony through Exercise: Aerobic exercise, a rhythmic symphony of motion, emerges as a potent strategy. A harmonious cadence of 30 minutes, at least five times a week, orchestrates a melody that harmonizes with blood pressure regulation.
    • The Nutritional Ensemble: The study’s findings echo the harmony of nutrients. Calcium, a stalwart companion to magnesium, unveils its prowess in blood pressure reduction. Consideration of supplements that intertwine calcium and magnesium could thus amplify health benefits.
    • The Ensemble Expands: The chorus of nutrients extends beyond calcium and magnesium. Coenzyme Q10 and Hawthorn, known for their cardiovascular contributions, stand as players in the symphony of blood pressure regulation. The resonance of beetroot juice, rich in nitrates that usher in nitric oxide release, unveils a unique path to vascular expansion and pressure reduction.
    • Tempering Sodium: The wise counsel of sodium moderation finds its place in this orchestration. The act of reducing sodium intake reverberates as a vital note in the melody of blood pressure management.

Harmonizing Health: Considerations and Caveats

As the crescendo of blood pressure management unfolds, certain considerations and caveats arise. The presence of chronic kidney disease, a pivotal factor, calls for prudence in magnesium supplementation. In these instances, magnesium’s impact can be counterproductive, necessitating a nuanced approach to wellness.

Conclusion

The study published in the American Journal of Clinical Nutrition marks a chapter in the ongoing saga of health exploration. Within its pages, magnesium emerges as a silent protagonist, wielding its influence over blood pressure regulation. As science and lifestyle interweave, a holistic approach to blood pressure management materializes. Weight reduction, exercise, nutrient supplementation, sodium moderation, and mindful practices converge to form the symphony of health. This composition holds the promise of resonant health, where the rhythm of life harmonizes with vitality.

References

American Journal of Clinical Nutrition (September, 2017)

http://ajcn.nutrition.org/content/106/3/921.abstract

Eat Smart, Live Well, Look Great,

Dr. Meschino

Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

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LMU 77 – The Vital Role of Coenzyme Q10: Energizing Your Body’s Powerhouse

LMU-77

LMU 77 – The Vital Role of Coenzyme Q10: Energizing Your Body's Powerhouse

Source: Multiple Source (see References Below)

Lifestyle Medicine Update (January 10, 2017)

Introduction:

In the intricate dance of life, there exists a substance that orchestrates energy production within our cells – Coenzyme Q10, often affectionately referred to as CoQ10. This vitamin-like entity emerges as a crucial cog in the machinery of our body, playing a pivotal role in transforming food into energy. Visualize it as a dedicated shuttle service that ferries hydrogen electrons through the cellular energy production factory, known as the mitochondria. As we venture into the realm of CoQ10, we uncover its significance, its connection to heart health, and the dynamic interplay between aging, medications, and this essential compound.

Fuelling the Energy Factory: The Role of Coenzyme Q10

Imagine your body as a complex automobile, with each cell serving as an engine. CoQ10 is akin to the fuel that ignites these engines, converting food into the energy required for cellular processes. This vitamin-like substance embarks on a journey within the cellular mitochondria, acting as a beacon of energy transformation. Just as a car with missing pistons sputters, cells with a CoQ10 deficiency falter in their energy production. A deficiency equates to reduced energy availability, akin to dimming the lights of vitality within our cells.

The Heart’s Cry: CoQ10 and Heart Health

While CoQ10’s impact reverberates throughout the body, it assumes a crucial role in the heart’s symphony. The heart, an ever-pulsating marvel, relies on a steady influx of energy to sustain its rhythmic contractions. Herein lies the heart of the matter – a deficiency in CoQ10 can spell trouble for the heart’s vigor. As this deficiency infiltrates the heart muscle, the energy production wanes, setting the stage for heart failure. In this scenario, the heart’s pumping mechanism weakens over time, leading to fluid accumulation in the lungs and extremities. This culminates in congestive heart failure, a grave condition that holds the mantle of being the leading cause of hospital admissions among individuals aged 65 and above.

Aging and the CoQ10 Connection

The passage of time leaves an indelible mark on CoQ10 levels within our bodies. As we journey through the years, our bodies gradually produce less CoQ10. This transformation becomes evident around the age of 45 to 50, where we produce less than half the amount synthesized in our vibrant 20s. The heart, an unwitting victim of this decline, reflects this diminished state, raising concerns about the potential risk of congestive heart failure. This revelation forms a clarion call for those approaching their 40s and beyond to consider fortifying their CoQ10 levels through supplementation.

Medications as CoQ10 Depleters

In the intricate tapestry of health, medications weave a complex narrative. Certain drugs, which serve as lifelines for various conditions, bear the unintended consequence of depleting CoQ10 levels. Statin drugs, wielded to lower cholesterol, stand as a prime example. These drugs curtail CoQ10 synthesis within the body, creating a paradox where the very agents designed to promote health inadvertently undermine it. Gemfibrozil, used to lower triglycerides, and specific medications aimed at managing high blood sugar and blood pressure, all fall within the realm of CoQ10 depleters.

Empowerment through Supplementation

In the quest for a vibrant and thriving life, empowerment emerges as a guiding light. For those navigating the landscape of aging, CoQ10 supplementation presents a beacon of hope. Experts in the realm of nutritional medicine, attuned to the symphony of health, advocate for CoQ10 supplementation after the age of 40. Doses ranging from 30 to 60 mg per day are often deemed sufficient to replenish the declining CoQ10 levels. Moreover, individuals taking medications that deplete CoQ10 should initiate a dialogue with their healthcare providers. Conversations revolving around increasing CoQ10 intake, in the range of 90 to 100 mg per day, hold the promise of safeguarding against the adverse effects linked to CoQ10 deficiency, notably congestive heart failure.

Conclusion

As we delve into the realm of Coenzyme Q10, the canvas of vitality unfurls before us. Within the depths of our cells, this unassuming entity ignites the flames of energy, propelling us forward in the dance of life. With every heartbeat and every pulse of energy, CoQ10 plays its part, a silent yet indispensable partner in our journey. As the pages of time turn and the spectre of aging looms, the tale of CoQ10’s decline unfolds. Yet, in this narrative, lies the promise of empowerment. Through supplementation and mindful consideration of medications, we stand poised to script our own story of vibrant living, fortifying our hearts and minds against the ravages of time.

References

  1. Kaikkonen J, Nyyssonen K, Tuomainen TP, et al.: Determinants of plasma coenzyme Q10 in humans. Federation of European Biochemical Societies Letters 443(2): 163-166, 1999.
  2. Thibault A, Samid D, Tompkins AC, et al.: Phase I study of lovastatin, an inhibitor of the mevalonate pathway, in patients with cancer. Clinical Cancer Research 2(3): 483-491, 1996.
  3. Pepping J: Coenzyme Q. American Journal of Health-System Pharmacy 56: 519-521, 1999.
 
Eat Smart, Live Well, Look Great,

Dr. Meschino

Introduction

In the intricate dance of life, there exists a substance that orchestrates energy production within our cells – Coenzyme Q10, often affectionately referred to as CoQ10. This vitamin-like entity emerges as a crucial cog in the machinery of our body, playing a pivotal role in transforming food into energy. Visualize it as a dedicated shuttle service that ferries hydrogen electrons through the cellular energy production factory, known as the mitochondria. As we venture into the realm of CoQ10, we uncover its significance, its connection to heart health, and the dynamic interplay between aging, medications, and this essential compound.

Fuelling the Energy Factory: The Role of Coenzyme Q10

Imagine your body as a complex automobile, with each cell serving as an engine. CoQ10 is akin to the fuel that ignites these engines, converting food into the energy required for cellular processes. This vitamin-like substance embarks on a journey within the cellular mitochondria, acting as a beacon of energy transformation. Just as a car with missing pistons sputters, cells with a CoQ10 deficiency falter in their energy production. A deficiency equates to reduced energy availability, akin to dimming the lights of vitality within our cells.

The Heart’s Cry: CoQ10 and Heart Health

While CoQ10’s impact reverberates throughout the body, it assumes a crucial role in the heart’s symphony. The heart, an ever-pulsating marvel, relies on a steady influx of energy to sustain its rhythmic contractions. Herein lies the heart of the matter – a deficiency in CoQ10 can spell trouble for the heart’s vigor. As this deficiency infiltrates the heart muscle, the energy production wanes, setting the stage for heart failure. In this scenario, the heart’s pumping mechanism weakens over time, leading to fluid accumulation in the lungs and extremities. This culminates in congestive heart failure, a grave condition that holds the mantle of being the leading cause of hospital admissions among individuals aged 65 and above.

Aging and the CoQ10 Connection

The passage of time leaves an indelible mark on CoQ10 levels within our bodies. As we journey through the years, our bodies gradually produce less CoQ10. This transformation becomes evident around the age of 45 to 50, where we produce less than half the amount synthesized in our vibrant 20s. The heart, an unwitting victim of this decline, reflects this diminished state, raising concerns about the potential risk of congestive heart failure. This revelation forms a clarion call for those approaching their 40s and beyond to consider fortifying their CoQ10 levels through supplementation.

Medications as CoQ10 Depleters

In the intricate tapestry of health, medications weave a complex narrative. Certain drugs, which serve as lifelines for various conditions, bear the unintended consequence of depleting CoQ10 levels. Statin drugs, wielded to lower cholesterol, stand as a prime example. These drugs curtail CoQ10 synthesis within the body, creating a paradox where the very agents designed to promote health inadvertently undermine it. Gemfibrozil, used to lower triglycerides, and specific medications aimed at managing high blood sugar and blood pressure, all fall within the realm of CoQ10 depleters.

Empowerment through Supplementation

In the quest for a vibrant and thriving life, empowerment emerges as a guiding light. For those navigating the landscape of aging, CoQ10 supplementation presents a beacon of hope. Experts in the realm of nutritional medicine, attuned to the symphony of health, advocate for CoQ10 supplementation after the age of 40. Doses ranging from 30 to 60 mg per day are often deemed sufficient to replenish the declining CoQ10 levels. Moreover, individuals taking medications that deplete CoQ10 should initiate a dialogue with their healthcare providers. Conversations revolving around increasing CoQ10 intake, in the range of 90 to 100 mg per day, hold the promise of safeguarding against the adverse effects linked to CoQ10 deficiency, notably congestive heart failure.

Conclusion

As we delve into the realm of Coenzyme Q10, the canvas of vitality unfurls before us. Within the depths of our cells, this unassuming entity ignites the flames of energy, propelling us forward in the dance of life. With every heartbeat and every pulse of energy, CoQ10 plays its part, a silent yet indispensable partner in our journey. As the pages of time turn and the spectre of aging looms, the tale of CoQ10’s decline unfolds. Yet, in this narrative, lies the promise of empowerment. Through supplementation and mindful consideration of medications, we stand poised to script our own story of vibrant living, fortifying our hearts and minds against the ravages of time.

References

  1. Kaikkonen J, Nyyssonen K, Tuomainen TP, et al.: Determinants of plasma coenzyme Q10 in humans. Federation of European Biochemical Societies Letters 443(2): 163-166, 1999.
  2. Thibault A, Samid D, Tompkins AC, et al.: Phase I study of lovastatin, an inhibitor of the mevalonate pathway, in patients with cancer. Clinical Cancer Research 2(3): 483-491, 1996.
  3. Pepping J: Coenzyme Q. American Journal of Health-System Pharmacy 56: 519-521, 1999.

Eat Smart, Live Well, Look Great,

Dr. Meschino

Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

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LMU 76 – Unveiling Nutritional Deficiencies in Aging: A Closer Look at Vitamin D, B12, and More

LMU-76

LMU 76 – Unveiling Nutritional Deficiencies in Aging: A Closer Look at Vitamin D, B12, and More

NMU 76 – Vitamin Deficiencies Common in Aging: How to identify them and prevent consequences

Lifestyle Medicine Update (December 20, 2017)

Introduction

As the pages of time turn and we venture into the realm of aging, an illuminating study beckons our attention, shedding light on the profound impact of nutritional deficiencies on our golden years. Published in the journal Nutrients in 2017, this study delves into the lives of an aging population in southern Germany, uncovering startling revelations about the prevalence of sub-optimal levels of essential micronutrients such as vitamin D, B12, iron, and folate. In this exploration, we unearth the significance of these deficiencies, their consequences, and the empowerment that lies within annual blood tests.

The Aging Enigma: Unveiling the KORA-Age Study

Encompassing the canvas of aging, the KORA-Age Study embarked on a mission to scrutinize the lives of 1,079 older adults, spanning from ages 65 to 93 years. This remarkable endeavor, undertaken by the KORA Cooperative Health Research platform, delved into the depths of four vital micronutrients – vitamin D, folate, vitamin B12, and iron. What emerged from this canvas of investigation was a tapestry of revelations, illuminating the prevalence of sub-optimal levels of these micronutrients in the aging populace.

Unmasking Vitamin D Insufficiency

The spotlight turns to vitamin D, a renowned ally in the battle against a myriad of ailments, from cancer to osteoporosis and diabetes. The study cast a revealing light, showcasing that over 50% of the examined older adults bore blood levels of vitamin D below 50 nmol/L, indicating a suboptimal status. This finding strikes a chord, considering the recommended level for optimal prevention stands at 75 nmol/L or higher. The research resonates as a cautionary tale, hinting at the need to address this prevalent deficiency to safeguard against the ravages of various health maladies.

Vitamin B12: A Memory’s Guardian

Vitamin B12, a sentinel for memory and cognition, takes center stage. The study unfurls a disconcerting truth – 27% of the elderly subjects bore blood levels of vitamin B12 below the established threshold. Beyond its role in preventing anemia, vitamin B12 wields its influence in the realms of memory and cognitive function. Its absence can unleash memory loss and dementia-related symptoms, as B12 plays a pivotal role in crafting brain neurotransmitters crucial for memory retention. This revelation underscores the imperative of addressing this deficiency early to preserve cognitive prowess and stave off the shadows of memory loss.

Folate and Iron: Guardians of Vitality

Folate and iron, unassuming yet vital players, unfurl their significance on this stage. The study exposes the sobering truth – 9% of participants grappled with low folate levels, while 11% bore the burden of low iron levels. These deficiencies are harbingers of subtle yet impactful consequences. Folate and vitamin B12 deficiencies herald memory loss and cognitive impairment, disrupting the delicate equilibrium of brain health. Iron, even in its marginal scarcity, can sow the seeds of low energy, memory lapses, concentration struggles, and weakened resistance to infections. These findings serve as a clarion call to address these deficiencies to preserve vitality and overall well-being.

Annual Blood Tests: A Beacon of Empowerment

In the realm of health, knowledge is power, and annual blood tests stand as the beacon of this empowerment. The study underscores the value of monitoring blood levels of these essential micronutrients. It beckons individuals to advocate for themselves, urging them to request comprehensive tests during their annual physical exams. While some insurance plans might not cover tests for vitamin D or homocysteine, their impact on health is immeasurable. The revelations these tests unveil provide a roadmap to potential future diseases, spurring individuals to take charge of their well-being.

The Path Forward: Nurturing Optimal Health

In the grand tapestry of life, aging is a chapter that deserves to be written with vibrancy, vitality, and resilience. The study’s findings echo a universal truth – to nurture health and well-being, one must be proactive. Regular monitoring of blood levels, particularly for vitamin D, B12, folate, iron, and homocysteine, holds the key to longevity and disease-free living. Armed with this knowledge, individuals can embrace the journey ahead with the assurance that their bodies and minds are fortified against the challenges of time.

Conclusion

As the curtain falls on the pages of this study, a narrative of empowerment emerges. The echoes of deficiency dissolve into the promise of proactive measures. The insights gained from this study transcend mere numbers, resonating as a call to action for all seeking a vibrant and thriving life. With the tapestry of aging before us, armed with the knowledge gleaned from annual blood tests, we can navigate the journey with vitality and resilience, embracing each chapter with the grace of well-nourished minds and bodies.

References

  1. Conzade R, et al. Prevalence and Predictors of Subclinical Micronutrient Deficiency in German Older Adults: Results from the Population-Based KORA-Age Study. Nutrients 2017, 9(12), 1276
  2. [Link to the Study] (http://www.mdpi.com/2072-6643/9/12/1276)

Eat Smart, Live Well, Look Great,

Dr. Meschino

Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

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LMU 75 – Ashwagandha: A Natural Stress Buster

LMU-75

LMU 75 – Ashwagandha: A Natural Stress Buster

Source: Indian Journal of Psychological Medicine (2012)

Lifestyle Medicine Update

Introduction

In a modern world that often teeters on the edge of chaos, stress has emerged as an unwelcome companion, weaving its way into the fabric of our lives and impacting both mental and physical health. The escalating prevalence of mental health disorders and the confluence of stress with physical ailments like ulcers, high blood pressure, and heart disease attest to its formidable influence. However, amidst the challenges, a beacon of hope shines through a captivating study published in the Indian Journal of Psychological Medicine in 2012. This study unveils the remarkable potential of an adaptogen herb called “Ashwagandha” to alleviate stress, enhance well-being, and even mitigate key biological markers of stress in individuals burdened by its weight.

The Vicious Cycle of Stress

Stress, stemming from external physical or mental burdens, casts a shadow that can engulf us in feelings of turmoil, anxiety, and unease. Prolonged exposure to stress serves as a catalyst, triggering a cascade of unbalanced mental and physiological states. The consequences extend beyond the emotional realm, ushering in a host of conditions ranging from depression to high blood pressure, heart disease, and metabolic disorders such as diabetes. These ailments, with their roots in mental and emotional factors, are surging in prevalence, emerging as significant global health challenges. In the face of this crisis, a growing fraction of the population seeks solace through medical intervention, striving to conquer the shackles of stress.

The Trailblazing Study: Ashwagandha’s Triumph

At the heart of this narrative rests a groundbreaking randomized controlled study that enrolled 64 participants afflicted by chronic stress. This study, meticulously crafted, summoned clinical examinations and laboratory tests to discern the impact of supplementation with Ashwagandha, an adaptogen herb renowned for its stress-modulating properties. The study delved into the abyss of subjective feelings of stress, objective biochemical markers, and vital well-being assessments. Half of the participants were administered a supplement containing 300 mg of Ashwagandha root extract standardized to 5% withanolide content, while the other half received a placebo.

The Power of Ashwagandha: Transformation Unveiled

The study’s findings read like a tale of transformation. After 60 days, subjects embraced by Ashwagandha experienced a surge of improvement in various dimensions, eclipsing the placebo group:

  • Feelings of Anxiety
  • Insomnia
  • Depression
  • Social Dysfunction

Akin to an enchanting spell, Ashwagandha wove its magic, inciting a marked reduction in blood cortisol levels – a direct reflection of the body’s stress response. This study stood as a testament to Ashwagandha’s ability to enact a resolute stand against stress, bolstering self-assessed quality of life for its recipients.

The Cortisol Conquest: A 30% Reduction

Cortisol, the renowned stress hormone, yielded to Ashwagandha’s might. The study showcased a jaw-dropping 28% reduction in cortisol levels within the Ashwagandha group. In contrast, the placebo group registered a mere 8% reduction. This staggering 30% decrease in cortisol levels attests to the profound influence of Ashwagandha in curbing the body’s stress-driven cortisol surge.

Beyond Stress: The Multidimensional Impact

The significance of this cortisol reduction ripples through the landscape of health. Elevated cortisol levels, often associated with chronic stress, pave the way for a range of adverse consequences:

    • Weakened Immune System – Leaving the body vulnerable to infections and even cancer, possibly triggering autoimmune diseases.
    • Ulcer Development – Fuelling the development of ulcers.
    • Increased High Blood Sugar – Elevating blood sugar levels.
    • Heightened Inflammation – Exacerbating inflammation, a precursor to numerous health woes.

Embracing Ashwagandha: A Vital Component of Stress Management

Researchers concluded with an unequivocal assertion that high-concentration full-spectrum Ashwagandha root extract empowers individuals to defy stress, elevating self-assessed quality of life. This adaptogen herb emerges as a safe and effective intervention for adults besieged by stress’s grasp.

A Holistic Approach to Stress Management

While Ashwagandha’s prowess offers a beacon of hope, it stands as part of a larger tapestry in stress management. It complements a holistic approach that embraces diverse strategies such as aerobic exercise, meditation, yoga, progressive relaxation, psychotherapy, and stress management. However, the potent ability of adaptogen herbs like Ashwagandha to recalibrate cortisol levels is a crucial facet in the pursuit of comprehensive well-being.

Conclusion

Amidst the cacophony of modern life, Ashwagandha emerges as a silent hero, bestowing the gift of stress alleviation. This research mirrors the transformative potential of harnessing nature’s treasures to combat the crippling weight of stress. While not a panacea, Ashwagandha’s capacity to tame cortisol levels is an invaluable tool in the quest for holistic health.

References

    1. Chandrasekhar K, Kapoor J, Anishetty S. A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults. Indian Journal of Psychological Medicine. 2012;34(3):255-262.
Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

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LMU 74 – Revolutionizing Blood Pressure Management: The Dominance of Diet

LMU-74

LMU 74 – Revolutionizing Blood Pressure Management: The Dominance of Diet

Source: American Journal of Cardiology (November 12, 2017)

Lifestyle Medicine Update (December 2, 2017)

Introduction:

In the dynamic realm of healthcare, a groundbreaking study, unveiled on November 12, 2017, within the pages of the Journal of the American College of Cardiology, shines a spotlight on a revolutionary dietary approach to lower high blood pressure. This monumental research asserts that this new dietary strategy can outpace the blood pressure-lowering effects of certain high blood pressure medications. This revelation underscores the potent impact of dietary interventions, encouraging healthcare providers to place heightened emphasis on proven dietary and lifestyle strategies when addressing patients with high blood pressure.

A Paradigm Shift: Dietary Dominance in Blood Pressure Control

While the importance of high blood pressure medications is undeniable, the research elucidates a fundamental shift in perspective. The study articulates that healthcare practitioners should magnify their focus on validated dietary and lifestyle interventions during consultations with high blood pressure patients. These interventions, the study contends, harbor the potential to render medication a secondary consideration in managing blood pressure.

Unveiling the Study: Dietary Marvel vs. North American Norms

The study’s canvas stretches across more than 400 patients grappling with stage-1 high blood pressure (hypertension). A pivotal divide emerged, with half of the participants engaging in the DASH diet, and the remaining half adhering to the quintessential North American diet, characterized by high fat content and refined carbohydrates. Both cohorts were further subjected to low-sodium, medium-sodium, or high-sodium diets over four-week intervals.

  • Low sodium = 1500 mg per day of sodium
  • Medium-sodium = 2,300 mg per day of sodium – equivalent to 1 teaspoon
  • High sodium = 3,450 mg per day of sodium

A teaspoon of table salt contains roughly 2400 mg of sodium. Notably, a sodium intake of 2300 mg per day (medium sodium intake) aligns with the U.S. Food and Drug Administration’s (FDA) recommended maximum level of sodium intake. Maintaining levels below this threshold is believed to mitigate the risk of heart disease and stroke.

The Study’s Revelation: Dietary Ascendance

The study’s findings are nothing short of revelatory. Participants who embraced the DASH diet alongside a low-sodium regimen (1500 mg sodium per day or less) exhibited a significant reduction in systolic blood pressure. This effect was particularly pronounced among individuals with higher initial blood pressure levels. Astonishingly, one participant with an initial systolic blood pressure exceeding 150 experienced a dramatic 21-point drop in just four weeks. The majority of participants experienced reductions between 5-10 points, a feat that echoes the stringent criterion for high-blood-pressure drug approval, which mandates a minimum 5-point blood pressure reduction. In contrast, the most efficacious high blood pressure-lowering medications typically yield an average reduction of 10-15 points in systolic blood pressure.

Decoding the DASH Diet: A Blueprint for Success

At the heart of this dietary revolution lies the DASH diet – an acronym for Dietary Approaches to Stop Hypertension. This dietary regimen champions a symphony of fruits, vegetables, whole grains, non-fat or low-fat dairy products, and lean meats, each characterized by low saturated and trans-fat content.

Dietary Intervention’s Triumph: Equivalent to Prescription Drugs

One researcher emphasized the significance of the combined dietary intervention, underscoring its potential to rival, or even surpass, the effects of prescription drugs. The study’s insights illuminate the comparable efficacy of dietary interventions and antihypertensive medications in high blood pressure management. This assertion assumes paramount importance for individuals at heightened risk of high blood pressure, advocating dietary interventions as a first-line treatment approach.

Elevating Empowerment: The Role of Prudent Dietary Practices

The study resounds with a potent message – individuals grappling with high blood pressure wield considerable power through prudent dietary choices. Anchored in dietary mindfulness, sodium reduction, weight management if needed, augmented endurance exercise, targeted supplement interventions, and meditation or relaxation therapies together compose a robust arsenal. For patients with systolic blood pressure at or below 150 mmHg, these strategies emerge as the frontline of treatment, either individually or in tandem with drug therapy. The intricacies deepen when patients possess complicating factors such as diabetes or other health conditions necessitating mandatory blood pressure medications. Even within this context, the study reinforces the integration of the diet and lifestyle strategies as integral facets of comprehensive management, fostering high blood pressure reduction and overall health enhancement.

Conclusion

The study’s proclamation transcends the boundaries of high blood pressure management, serving as a clarion call for the ascendance of dietary interventions. In an era where the allure of medications often overshadows the potential of lifestyle modifications, this research underscores the paramount importance of dietary empowerment. The implications reverberate across medical landscapes, fostering a transformational shift towards harnessing the potential of dietary choices to herald health and vitality.

High Blood Pressure

References

  1. https://www.sciencedaily.com/releases/2017/11/171122131412.htm 
  2. Stephen P. Juraschek, Edgar R. Miller, Connie M. Weaver, Lawrence J. Appel. Effects of Sodium Reduction and the DASH Diet in Relation to Baseline Blood Pressure. Journal of the American College of Cardiology, 2017;
  3. DASH Diet: https://www.nhlbi.nih.gov/files/docs/public/heart/new_dash.pdf
 
Eat Smart, Live Well, Look Great,

Dr. Meschino

Introduction

In the dynamic realm of healthcare, a groundbreaking study, unveiled on November 12, 2017, within the pages of the Journal of the American College of Cardiology, shines a spotlight on a revolutionary dietary approach to lower high blood pressure. This monumental research asserts that this new dietary strategy can outpace the blood pressure-lowering effects of certain high blood pressure medications. This revelation underscores the potent impact of dietary interventions, encouraging healthcare providers to place heightened emphasis on proven dietary and lifestyle strategies when addressing patients with high blood pressure.

A Paradigm Shift: Dietary Dominance in Blood Pressure Control

While the importance of high blood pressure medications is undeniable, the research elucidates a fundamental shift in perspective. The study articulates that healthcare practitioners should magnify their focus on validated dietary and lifestyle interventions during consultations with high blood pressure patients. These interventions, the study contends, harbor the potential to render medication a secondary consideration in managing blood pressure.

Unveiling the Study: Dietary Marvel vs. North American Norms

The study’s canvas stretches across more than 400 patients grappling with stage-1 high blood pressure (hypertension). A pivotal divide emerged, with half of the participants engaging in the DASH diet, and the remaining half adhering to the quintessential North American diet, characterized by high fat content and refined carbohydrates. Both cohorts were further subjected to low-sodium, medium-sodium, or high-sodium diets over four-week intervals.

  • Low sodium = 1500 mg per day of sodium
  • Medium-sodium = 2,300 mg per day of sodium – equivalent to 1 teaspoon
  • High sodium = 3,450 mg per day of sodium

A teaspoon of table salt contains roughly 2400 mg of sodium. Notably, a sodium intake of 2300 mg per day (medium sodium intake) aligns with the U.S. Food and Drug Administration’s (FDA) recommended maximum level of sodium intake. Maintaining levels below this threshold is believed to mitigate the risk of heart disease and stroke.

The Study’s Revelation: Dietary Ascendance

The study’s findings are nothing short of revelatory. Participants who embraced the DASH diet alongside a low-sodium regimen (1500 mg sodium per day or less) exhibited a significant reduction in systolic blood pressure. This effect was particularly pronounced among individuals with higher initial blood pressure levels. Astonishingly, one participant with an initial systolic blood pressure exceeding 150 experienced a dramatic 21-point drop in just four weeks. The majority of participants experienced reductions between 5-10 points, a feat that echoes the stringent criterion for high-blood-pressure drug approval, which mandates a minimum 5-point blood pressure reduction. In contrast, the most efficacious high blood pressure-lowering medications typically yield an average reduction of 10-15 points in systolic blood pressure.

Decoding the DASH Diet: A Blueprint for Success

At the heart of this dietary revolution lies the DASH diet – an acronym for Dietary Approaches to Stop Hypertension. This dietary regimen champions a symphony of fruits, vegetables, whole grains, non-fat or low-fat dairy products, and lean meats, each characterized by low saturated and trans-fat content.

Dietary Intervention’s Triumph: Equivalent to Prescription Drugs

One researcher emphasized the significance of the combined dietary intervention, underscoring its potential to rival, or even surpass, the effects of prescription drugs. The study’s insights illuminate the comparable efficacy of dietary interventions and antihypertensive medications in high blood pressure management. This assertion assumes paramount importance for individuals at heightened risk of high blood pressure, advocating dietary interventions as a first-line treatment approach.

Elevating Empowerment: The Role of Prudent Dietary Practices

The study resounds with a potent message – individuals grappling with high blood pressure wield considerable power through prudent dietary choices. Anchored in dietary mindfulness, sodium reduction, weight management if needed, augmented endurance exercise, targeted supplement interventions, and meditation or relaxation therapies together compose a robust arsenal. For patients with systolic blood pressure at or below 150 mmHg, these strategies emerge as the frontline of treatment, either individually or in tandem with drug therapy. The intricacies deepen when patients possess complicating factors such as diabetes or other health conditions necessitating mandatory blood pressure medications. Even within this context, the study reinforces the integration of the diet and lifestyle strategies as integral facets of comprehensive management, fostering high blood pressure reduction and overall health enhancement.

Conclusion

The study’s proclamation transcends the boundaries of high blood pressure management, serving as a clarion call for the ascendance of dietary interventions. In an era where the allure of medications often overshadows the potential of lifestyle modifications, this research underscores the paramount importance of dietary empowerment. The implications reverberate across medical landscapes, fostering a transformational shift towards harnessing the potential of dietary choices to herald health and vitality.

High Blood Pressure

References

  1. https://www.sciencedaily.com/releases/2017/11/171122131412.htm
  2. Stephen P. Juraschek, Edgar R. Miller, Connie M. Weaver, Lawrence J. Appel. Effects of Sodium Reduction and the DASH Diet in Relation to Baseline Blood Pressure. Journal of the American College of Cardiology, 2017;
  3. DASH Diet: https://www.nhlbi.nih.gov/files/docs/public/heart/new_dash.pdf

Eat Smart, Live Well, Look Great,

Dr. Meschino

Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

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LMU 73 – Unleashing Dietary Power: Navigating Rheumatoid Arthritis and Beyond

LMU-73

LMU 73 – Unleashing Dietary Power: Navigating Rheumatoid Arthritis and Beyond

Source: Journal Frontiers in Nutrition – Clinical Nutrition (November 2017)

Lifestyle Medicine Update (November 24, 2017)

Introduction:

In the realm of health and wellness, the profound impact of diet on various medical conditions is garnering increasing attention. One such condition, rheumatoid arthritis (RA), has spurred researchers to unravel the intricate relationship between dietary practices and disease management. A research review paper, published in the esteemed journal Frontiers in Nutrition on November 8, 2017, unfurls a tapestry of insights into the role of dietary interventions in the management of RA. While the focus is on RA, the implications extend to other autoimmune joint conditions and even osteoarthritis, laying the foundation for a holistic approach to health.

From Insights to Implications: An Overview

The research review paper embarked on a comprehensive journey through dietary practices, drawing on a myriad of studies to weave a compelling narrative. At its core lies a set of recommendations that seeks to ameliorate symptoms and curb disease progression through dietary choices. While the paper’s spotlight is on RA, its far-reaching recommendations hold promise for an array of degenerative diseases.

The Journey Begins: Dietary Approaches for RA

The canvas of dietary interventions for RA is painted with diverse strokes, each representing a distinct approach. Among these stands the “7-Day Supervised Fast,” an approach that segues into an ongoing vegan diet. This intervention offers limited vitamin and mineral supplementation, carbohydrate intake, and energy derived from vegetable juice over a week. Remarkably, this regimen engenders a decrease in the activation of CD4 cells, inhibiting the inflammatory TH1 and Th17 cells, notorious for their role in triggering inflammation and joint deterioration in RA. Not stopping there, this approach also ushers in a reduction in other inflammatory joint chemicals such as LTB4, stemming from neutrophils. In an intriguing turn, the diet induces ketosis, a state of low-blood sugar. Within this metabolic shift, a ketone body – beta-hydroxybutyric acid – emerges as a potent force, mitigating the secretion of cytokines, the inflammation-inducing chemicals that often run rampant in RA. The combined effects of this regimen showcase its potential to assuage inflammation, pain, and joint destruction, offering a glimmer of hope amidst the challenge of RA.

Mediterranean Marvel: Diet as a Shield

Amidst the dietary landscape, the Mediterranean diet surfaces as a beacon of promise. This dietary approach, rich in oleic acid, omega-3 fatty acids, unrefined carbohydrates, and phytochemicals, encompasses a diet high in olive oil, cereals, fruits, vegetables, fish, and legumes. The inclusion of moderate amounts of red wine further elevates its allure. Within this tapestry of consumption, olive oil and fish emerge as stalwart warriors against inflammation, underpinning its potential to stave off the onset of RA.

Diving Deeper: Elemental Diet and Elimination Diet

A more formidable path unveils itself in the form of the Elemental Diet. Comprising a liquid formula enriched with specific amino acids, minimal glucose, and essential vitamins and trace elements, this regimen demonstrated its potency in a large study. A staggering 72% of patients registered over 20% improvement in pain and early morning stiffness, underscoring its potential in curbing RA symptoms. The hypoallergenic nature of this formula further underscores its efficacy in managing immune system overactivity.

The Elimination Diet, in turn, embraces a personalized approach. It seeks to identify and eliminate foods that trigger sensitivity in individuals. This tailored strategy acknowledges the tendency of food-based antigens to seep through the gut and incite an immune-inflammatory response, exacerbating RA symptoms.

The Culmination: Researcher Recommendations

Having traversed a spectrum of dietary interventions, the research review paper culminates in a set of recommendations tailored for RA patients. The ideal meal envisioned by the researchers encompasses raw or moderately cooked vegetables, replete with greens and legumes. The infusion of spices like turmeric and ginger, coupled with seasonal fruits and probiotic yogurt, orchestrates a symphony of natural antioxidants and anti-inflammatory effects. In tandem, the exclusion of processed foods, excessive salt, oils, butter, sugar, and animal products constitutes a pivotal facet. The researchers further advocate for dietary supplements such as vitamin D, cod liver oil, and multivitamins. These dietary practices, when harmoniously paired with low-impact aerobic exercises, present a formidable framework for self-managing RA, rendering it a financially sustainable endeavor.

The Science of Healing: Harnessing Nature’s Arsenal

The research review paper delves into the realm of scientific substantiation, underscoring the anti-inflammatory properties of a multitude of natural compounds. Green tea catechins, ginger, curcumin (derived from turmeric), boswellia, ashwagandha, and cinnamon bark emerge as warriors against inflammation. Grapes, oranges, apples, tomatoes, spinach, and potatoes, teeming with p-Coumaric acid, also manifest potent anti-inflammatory effects. The isoflavone genistein found in soybeans joins the fray, further enhancing the armament against inflammation. Omega-3 fats and borage seed oil, rich in gamma-linolenic acid, add their names to the roster of inflammation fighters. The canvas expands to encompass prebiotics and probiotics, yielding not only anti-inflammatory effects but also antioxidant properties. This twofold impact is underscored by their ability to shape gut microflora and modulate the immune system.

A Universal Approach: Beyond RA

While the research review paper’s focal point is RA, its insights ripple across the healthcare landscape. The dietary approach advocated within its pages resonates as a potent strategy in averting and managing a spectrum of degenerative diseases – from heart disease to Alzheimer’s disease. The pursuit of health, through conscientious dietary choices, emerges as a unifying thread woven through diverse medical narratives.

Conclusion

In the realm of health, the research review paper in question transcends a singular condition, urging readers to explore the dynamic interplay between diet and disease management. The insights unveiled within its pages, anchored by comprehensive studies and expert recommendations, hold the potential to transform lives. Beyond rheumatoid arthritis, this dietary approach extends its embrace to a tapestry of ailments, urging individuals to harness the power of nutrition in their journey towards vitality.

Reference

Khanna S, Jaiswal KS and Gupta B. Managing rheumatoid arthritis with dietary interventions. Frontiers in Nutrition – Clinical Nutrition. November 8, 2017.
https://www.frontiersin.org/articles/10.3389/fnut.2017.00052/full


Eat Smart, Live Well, Look Great

Dr. Meschino

Introduction

In the realm of health and wellness, the profound impact of diet on various medical conditions is garnering increasing attention. One such condition, rheumatoid arthritis (RA), has spurred researchers to unravel the intricate relationship between dietary practices and disease management. A research review paper, published in the esteemed journal Frontiers in Nutrition on November 8, 2017, unfurls a tapestry of insights into the role of dietary interventions in the management of RA. While the focus is on RA, the implications extend to other autoimmune joint conditions and even osteoarthritis, laying the foundation for a holistic approach to health.

From Insights to Implications: An Overview

The research review paper embarked on a comprehensive journey through dietary practices, drawing on a myriad of studies to weave a compelling narrative. At its core lies a set of recommendations that seeks to ameliorate symptoms and curb disease progression through dietary choices. While the paper’s spotlight is on RA, its far-reaching recommendations hold promise for an array of degenerative diseases.

The Journey Begins: Dietary Approaches for RA

The canvas of dietary interventions for RA is painted with diverse strokes, each representing a distinct approach. Among these stands the “7-Day Supervised Fast,” an approach that segues into an ongoing vegan diet. This intervention offers limited vitamin and mineral supplementation, carbohydrate intake, and energy derived from vegetable juice over a week. Remarkably, this regimen engenders a decrease in the activation of CD4 cells, inhibiting the inflammatory TH1 and Th17 cells, notorious for their role in triggering inflammation and joint deterioration in RA. Not stopping there, this approach also ushers in a reduction in other inflammatory joint chemicals such as LTB4, stemming from neutrophils. In an intriguing turn, the diet induces ketosis, a state of low-blood sugar. Within this metabolic shift, a ketone body – beta-hydroxybutyric acid – emerges as a potent force, mitigating the secretion of cytokines, the inflammation-inducing chemicals that often run rampant in RA. The combined effects of this regimen showcase its potential to assuage inflammation, pain, and joint destruction, offering a glimmer of hope amidst the challenge of RA.

Mediterranean Marvel: Diet as a Shield

Amidst the dietary landscape, the Mediterranean diet surfaces as a beacon of promise. This dietary approach, rich in oleic acid, omega-3 fatty acids, unrefined carbohydrates, and phytochemicals, encompasses a diet high in olive oil, cereals, fruits, vegetables, fish, and legumes. The inclusion of moderate amounts of red wine further elevates its allure. Within this tapestry of consumption, olive oil and fish emerge as stalwart warriors against inflammation, underpinning its potential to stave off the onset of RA.

Diving Deeper: Elemental Diet and Elimination Diet

A more formidable path unveils itself in the form of the Elemental Diet. Comprising a liquid formula enriched with specific amino acids, minimal glucose, and essential vitamins and trace elements, this regimen demonstrated its potency in a large study. A staggering 72% of patients registered over 20% improvement in pain and early morning stiffness, underscoring its potential in curbing RA symptoms. The hypoallergenic nature of this formula further underscores its efficacy in managing immune system overactivity.

The Elimination Diet, in turn, embraces a personalized approach. It seeks to identify and eliminate foods that trigger sensitivity in individuals. This tailored strategy acknowledges the tendency of food-based antigens to seep through the gut and incite an immune-inflammatory response, exacerbating RA symptoms.

The Culmination: Researcher Recommendations

Having traversed a spectrum of dietary interventions, the research review paper culminates in a set of recommendations tailored for RA patients. The ideal meal envisioned by the researchers encompasses raw or moderately cooked vegetables, replete with greens and legumes. The infusion of spices like turmeric and ginger, coupled with seasonal fruits and probiotic yogurt, orchestrates a symphony of natural antioxidants and anti-inflammatory effects. In tandem, the exclusion of processed foods, excessive salt, oils, butter, sugar, and animal products constitutes a pivotal facet. The researchers further advocate for dietary supplements such as vitamin D, cod liver oil, and multivitamins. These dietary practices, when harmoniously paired with low-impact aerobic exercises, present a formidable framework for self-managing RA, rendering it a financially sustainable endeavor.

The Science of Healing: Harnessing Nature’s Arsenal

The research review paper delves into the realm of scientific substantiation, underscoring the anti-inflammatory properties of a multitude of natural compounds. Green tea catechins, ginger, curcumin (derived from turmeric), boswellia, ashwagandha, and cinnamon bark emerge as warriors against inflammation. Grapes, oranges, apples, tomatoes, spinach, and potatoes, teeming with p-Coumaric acid, also manifest potent anti-inflammatory effects. The isoflavone genistein found in soybeans joins the fray, further enhancing the armament against inflammation. Omega-3 fats and borage seed oil, rich in gamma-linolenic acid, add their names to the roster of inflammation fighters. The canvas expands to encompass prebiotics and probiotics, yielding not only anti-inflammatory effects but also antioxidant properties. This twofold impact is underscored by their ability to shape gut microflora and modulate the immune system.

A Universal Approach: Beyond RA

While the research review paper’s focal point is RA, its insights ripple across the healthcare landscape. The dietary approach advocated within its pages resonates as a potent strategy in averting and managing a spectrum of degenerative diseases – from heart disease to Alzheimer’s disease. The pursuit of health, through conscientious dietary choices, emerges as a unifying thread woven through diverse medical narratives.

Conclusion

In the realm of health, the research review paper in question transcends a singular condition, urging readers to explore the dynamic interplay between diet and disease management. The insights unveiled within its pages, anchored by comprehensive studies and expert recommendations, hold the potential to transform lives. Beyond rheumatoid arthritis, this dietary approach extends its embrace to a tapestry of ailments, urging individuals to harness the power of nutrition in their journey towards vitality.

Reference

Khanna S, Jaiswal KS and Gupta B. Managing rheumatoid arthritis with dietary interventions. Frontiers in Nutrition – Clinical Nutrition. November 8, 2017.
https://www.frontiersin.org/articles/10.3389/fnut.2017.00052/full

Eat Smart, Live Well, Look Great

Dr. Meschino

Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

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LMU 72 – Unveiling the Power to Prevent Diabetes: A Path Forward for Canadians

LMU-72

LMU 72 – Unveiling the Power to Prevent Diabetes: A Path Forward for Canadians

Source: Journal American Medical Association – Internal Medicine (November 2017)

Lifestyle Medicine Update (November 17, 2017)

Introduction

In the heart of Canada’s health landscape, a concerning reality unfolds – a staggering 2 million individuals grapple with diabetes, while an additional 7 million teeter on the brink of pre-diabetes, a harbinger of future health woes. This staggering statistic encompasses almost a third of the population, shedding light on the urgent need for intervention. Pre-diabetes, marked by fasting glucose levels ranging from 5.7 to 6.9 mmol/L, often accompanies other risk factors such as excessive abdominal fat, elevated blood pressure, high triglycerides, or low HDL-cholesterol. These statistics resonate beyond borders, as the U.S. mirrors a similar narrative with a diabetic and pre-diabetic cohort totalling a staggering 100 million individuals. In the U.S., a notable 9.4% of the population already battles diabetes. The magnitude of this issue necessitates exploration, as a study published in JAMA Internal Medicine sets the stage for a potential paradigm shift in diabetes prevention strategies.

The Looming Menace: Pre-diabetes and Diabetes in Canada

Within Canada’s diverse fabric lies an alarming health challenge, one that involves a significant portion of the populace. With 2 million diabetics and 7 million individuals navigating the precipice of pre-diabetes, equivalent to almost a third of the population, the threat looms large. Pre-diabetes is not merely an isolated numeric range; it is accompanied by a constellation of risk factors. Abdominal fat, as indicated by a waist circumference exceeding 36 inches for men and 33 inches for women, casts its ominous shadow. The presence of high blood pressure, elevated triglyceride levels, or diminished HDL-cholesterol further compounds the predicament. Such an intricate landscape beckons for innovative interventions.

The Quest for Prevention: A Meta-analysis Unveiled

Amidst this health landscape, a study published on November 6, 2017, in JAMA Internal Medicine resounds with hope. This meta-analysis of 43 international studies delved into the realm of pre-diabetes, aiming to uncover strategies that thwart its evolution into full-blown diabetes. The study resoundingly affirms the paramount importance of lifestyle modifications in this pursuit. Shedding those extra pounds surfaces as the cornerstone, as each kilogram of weight loss correlates with a remarkable 7% reduction in diabetes risk progression. The analysis embraced 43 studies, collectively revealing that lifestyle changes, from dietary adjustments to exercise, emerge as the most potent armament against the looming threat.

The Vanguard of Change: Lifestyle Modification

Within the 19 trials centred on lifestyle modification, an average treatment span of 2.6 years illuminated compelling outcomes. Patients who embraced dietary changes, exercise, or a combination thereof, charted a remarkable 39% lower risk of diabetes diagnosis compared to their non-intervention counterparts. The synergy of dietary adjustments and physical activity materialized as the optimal strategy, boasting a 41% risk reduction. This revelation encapsulates the dynamic interplay of nutrition and movement in diabetes prevention.

Medication as a Contender: A Parallel Perspective

Parallelly, the 21 medication trials provided intriguing insights. Over an average treatment duration of 3.1 years, medication recipients exhibited a commendable 36% lower risk of diabetes diagnosis in contrast to individuals randomized to control groups. This underscores the potential of pharmaceutical interventions to complement lifestyle modifications.

Sustaining Success: Long-term Implications

Beyond immediate interventions lies the critical question of sustainability. When formal lifestyle treatment was paused, patients who had embraced lifestyle modifications enjoyed a sustained 28% reduction in diabetes risk after a mean follow-up of 7.2 years. In stark contrast, individuals who underwent medication-induced washout exhibited no discernible reduction in diabetes risk post a mean 17-week follow-up. This underscored the long-term efficacy of lifestyle modifications in sustaining risk reduction.

Harnessing the Power of Prevention

The crux of the matter lies in the realization that a significant portion of the population hovers on the edge of diabetes due to incremental body fat and creeping blood sugar levels. The toll exacted by diabetes is immense – a shortened lifespan, heightened risk of debilitating complications including amputations, blindness, and the need for frequent dialysis. The perils extend to increased vulnerability to heart attacks, peripheral neuropathy, foot pain, and open foot wounds. It’s a burden too heavy to bear.

A Simple Solution: The Mathematics of Change

In the realm of diabetes prevention, simplicity is key. The arithmetic is straightforward – a mere reduction of 100 calories in daily intake coupled with an extra 100 calories burned through a brisk 10-12-minute walk can translate into the loss of 24 pounds of body fat in one year. This equation holds true for everyone, irrespective of their metabolism. Thus, for those perched on the cusp of diabetes, the promise of transformation lies in simple nutritional tweaks and increased physical activity. These seemingly modest adjustments possess the power to reverse major risk factors – from blood glucose levels and waist circumference to triglycerides, blood pressure, and HDL-cholesterol.

A Call to Action

The studies showcased within these findings ring loud and clear: individuals possess the authority to curb the ascent of diabetes and its life-altering complications. Empowerment lies in lifestyle modifications, a realm where the fusion of dietary choices and movement leads the charge.

Conclusion

The chronicle of diabetes and pre-diabetes in Canada encapsulates a significant health challenge. Yet, within this challenge resides the potential for transformation. The insights gleaned from the JAMA Internal Medicine study etch a path forward, one guided by lifestyle modifications, weight loss, and sustained commitment. The rallying cry is clear – harness the power of prevention and seize control over the trajectory of your health.

Reference

Haw SJ, Glalaviz KI, Straus AN. Long-term sustainability of diabetes prevention approaches. A systematic review and meta-analysis of randomized clinical trials. JAMA – Internal Medicine (November 6, 2017).
https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2661704

Eat Smart, Live Well, Look Great,

Dr. Meschino

Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

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LMU – 71 Unlocking Liver Health: The Synergistic Impact of Probiotics, Omega-3 Fats, and Vitamin E

LMU-71

LMU – 71 Unlocking Liver Health: The Synergistic Impact of Probiotics, Omega-3 Fats, and Vitamin E

Source: United European Gastroenterology (UEG) Week 2017. Presented November 1, 2017

Lifestyle Medicine Update (November 10, 2017)

Introduction

In the landscape of modern health challenges, the prevalence of fatty liver disease has emerged as a significant concern, paralleling the rising rates of overweight problems, obesity, and type 2 diabetes. Characterized by inflammation and fat accumulation within the liver, this condition, medically referred to as “steatohepatitis,” poses a dual threat in the forms of alcoholic and non-alcoholic fatty liver diseases. The latter, commonly termed non-alcoholic steatohepatitis (NASH), is closely linked to obesity, diabetes, and metabolic syndrome. The progression of either manifestation to cirrhosis, an irreversible and life-threatening liver disease, has intensified the search for effective interventions. Enter nutritional medicine, where recent studies are revealing the potential synergy of vitamin E, probiotics, and omega-3 fats in combatting this menacing ailment.

The Rise of Fatty Liver Disease

As modern lifestyles become increasingly sedentary and dietary habits tend toward excess, a surge in overweight problems, obesity, and type 2 diabetes has been witnessed. In lockstep with these trends, the incidence of fatty liver disease, or steatohepatitis, has climbed, bringing to light the dire consequences of unchecked metabolic disturbances. Steatohepatitis encompasses inflammation and fat accumulation within the liver, a condition not solely confined to alcoholics. Its non-alcoholic variant, NASH, manifests in individuals with diabetes, obesity, and metabolic syndrome, representing a pre-diabetic state. Of utmost concern is the propensity of both forms to escalate into cirrhosis, an irreversible and life-threatening liver condition.

A Glimmer of Hope: Vitamin E and Fatty Liver

In 2012, a pivotal shift in treatment recommendations occurred when the American Association for the Study of Liver Diseases, the American College of Gastroenterology, and the American Gastroenterological Association endorsed the supplementation of vitamin E for fatty liver problems. This marked a significant step towards harnessing nutritional interventions to mitigate liver-related challenges.

The Emerging Trio: Probiotics, Omega-3 Fats, and Liver Health

In a twist of fate, a recent study has surfaced, unveiling a potent combination that could help reverse liver damage in patients afflicted by non-alcoholic fatty liver disease (NAFLD). This groundbreaking trial focused on 48 adults grappling with NAFLD, some of whom were also burdened by type 2 diabetes. The intervention involved administering a fusion of probiotics and omega-3 fats from flaxseed and wheat germ oil for a span of eight weeks, while a placebo group was concurrently monitored. The findings unveiled a remarkable reduction in the mean fatty liver index score, a comprehensive indicator encompassing various blood markers that signify liver inflammation and damage. Furthermore, this revelation was not an isolated incident; prior animal studies had already hinted at the symbiotic relationship between probiotics and omega-3 fats, echoing the outcomes of the present human trial.

The Microbial Symphony: Probiotics’ Role

The significance of probiotics, often colloquially referred to as “friendly bacteria,” cannot be understated. Their pivotal role in fostering a harmonious gut microbiome is believed to wield a twofold impact: suppressing the release of inflammation-promoting chemicals by less amicable bacterial entities and potentially secreting beneficial substances that traverse the bloodstream and exert protective effects on the liver. This dual-pronged mechanism underlines the capacity of probiotics to modulate liver health at its core.

Omega-3 Fats: A Multi-Faceted Shield

The inclusion of omega-3 fats in this liver-boosting equation introduces a multifaceted layer of protection. Known for their ability to impede cell division and curb inflammation, omega-3 fats present a mechanism that holds promise in the reduction of cirrhosis development and the reversal of fibrotic damage in liver cells. This is just one facet of their comprehensive impact on overall health and disease management.

The Promise of Nutritional Medicine

The convergence of probiotics, omega-3 fats, and vitamin E as potent tools in the battle against non-alcoholic fatty liver disease underscores the influence of nutritional medicine in both disease prevention and complementary management. The foundation laid by research in this realm speaks volumes about the intrinsic connection between the foods we consume, the exercise we engage in, and the supplements we choose to integrate into our lives, and the modulation of our health and healthy life expectancy.

A Glimpse into the Future

While the current findings shine a light on the potent partnership between probiotics, omega-3 fats, and vitamin E, the journey of discovery continues. As the scientific community delves deeper into the intricacies of liver health, it is likely that additional mechanisms through which these interventions exert their effects will be unearthed. The tantalizing potential of these nutritional powerhouses in shaping liver function invites further exploration and innovation in the field of medical science.

Conclusion

In a world grappling with escalating rates of fatty liver disease, the convergence of nutritional medicine and scientific inquiry offers a glimmer of hope. The triumphant trio of probiotics, omega-3 fats, and vitamin E emerges as a formidable ally in the war against non-alcoholic fatty liver disease. The potential to reverse damage and enhance liver health through these interventions speaks to the profound impact of lifestyle choices and dietary supplementation. As researchers continue to unearth the underlying mechanisms driving these effects, the horizon of possibilities in liver health management expands, marking yet another triumph for the realm of nutritional medicine.

References

  1. American Association for the Study of Liver Diseases. (2012). Vitamin E and Fatty Liver Disease. Retrieved from
    https://www.aasld.org/sites/default/files/2020-02/Vitamin%20E%20and%20Fatty%20Liver%20Disease.pdf
  2. Medscape. (2017). Probiotics, Omega-3s Reverse Fatty Liver Disease. Retrieved from
    https://www.medscape.com/viewarticle/887955?nlid=118860_1842&src=WNL_mdplsfeat_171107_mscpedit_wir&uac=62515BJ&spon=17&impID=1476698&faf=1
  3. Mayo Clinic. (2023). Non-alcoholic Fatty Liver Disease. Retrieved from
    https://www.mayoclinic.org/diseases-conditions/nonalcoholic-fatty-liver-disease/symptoms-causes/syc-20354567

Eat Smart, Live Well, Look Great,

Dr. Meschino

Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

Adeeva Supplements
Posted on by

LMU 70 – Unlocking the Healing Power of Vitamin E: A Breakthrough for Fatty Liver Disease

LMU-70

LMU 70 – Unlocking the Healing Power of Vitamin E: A Breakthrough for Fatty Liver Disease

Source: Journal Hepatology 2012

Lifestyle Medicine Update (November 2, 2017)

Introduction: A Growing Epidemic Beckons Attention

In the ever-evolving landscape of medical research, revelations unfold, casting light on once-hidden corners of human health. Among the concerns that have surged to the forefront is Fatty Liver Disease, a condition that has stealthily grown alongside the obesity and type 2 diabetes epidemic. This condition, scientifically known as “steatohepatitis,” is a twofold menace, involving inflammation and fat accumulation within the liver. As medical bodies like the American Association for the Study of Liver Diseases, the American College of Gastroenterology, and the American Gastroenterological Association gather insights, fresh guidelines emerge to reshape the landscape of Fatty Liver Disease treatment.

Fatty Liver Disease: Navigating the Terrain

While Fatty Liver Disease has long been linked to excessive alcohol consumption, an alarming variant has surfaced among non-alcoholic individuals, known as non-alcoholic steatohepatitis (NASH). This form finds a comfortable home in those wrestling with diabetes, obesity, and metabolic syndrome. United by their vulnerability, both incarnations of Fatty Liver Disease harbor the potential to escalate into cirrhosis, a menacing liver condition that reverberates with life-threatening echoes.

Vitamin E’s Astonishing Role: Rewriting the Script of Liver Health

Amidst this backdrop, a ray of hope emerges, one that bears the name of an unassuming vitamin – E. The 2012 guidelines issued by leading medical associations encompassing the American Association for the Study of Liver Diseases, the American College of Gastroenterology, and the American Gastroenterological Association cast a spotlight on the potential of Vitamin E in tackling Fatty Liver Disease. Encouraging patients with NASH to embark on a journey of excess body fat reduction and alcohol avoidance, these guidelines transcend the ordinary by advocating the provision of 800 IU of vitamin E daily.

The resonance of this recommendation reverberates through studies that have illuminated Vitamin E’s unique ability to reverse liver cell damage, breathing new life into the histological features of liver cells in NASH cases. The implications are profound; Vitamin E emerges as a trailblazing pharmacotherapy, poised to tackle the very fabric of fatty liver issues at the cellular level.

Unravelling a Lifeline: The Power of Vitamin E in Preventing Cirrhosis

This revelation is no mere academic insight. In a realm where few agents possess the prowess to reverse non-alcoholic steatohepatitis-induced liver damage, Vitamin E stands tall as a beacon of hope. The potential to stall the harrowing progression of Fatty Liver Disease to the relentless grasp of cirrhosis marks Vitamin E as a vital guardian, a line of defence against an irreversible liver condition.

Beyond the Surface: Vitamin E’s Ripple Effect

The story takes an intriguing twist, unfolding to reveal yet another facet of Vitamin E’s impact. Recent revelations have unveiled Vitamin E’s hand in curbing the risk of liver cancer, hepatocellular carcinoma, particularly in high-risk individuals. This finding, chronicled in the Journal of the National Cancer Institute, underscores Vitamin E’s multi-dimensional influence, extending its healing touch beyond the realms of Fatty Liver Disease.

Heed the Call: A Path to Wellness

For those navigating the labyrinth of health marked by high triglyceride levels, elevated liver enzymes, and an undertone of fatty liver woes, a crucial dialogue with healthcare providers awaits. The pursuit of 800 IU of Vitamin E daily beckons as a potential lifeline, a stride toward thwarting the relentless progression of liver damage. But Vitamin E is not a solitary warrior; it dances in tandem with a tapestry of dietary and lifestyle modifications that coalesce to foster well-being.

Charting a Course with Insights: Embrace the Journey

As the pages of medical journals turn, revealing Vitamin E’s hidden potential in Fatty Liver Disease treatment, individuals are bestowed with a unique opportunity. In a world marked by uncertainties, Vitamin E emerges as a steady guide, an advocate for liver health, and a herald of hope. The journey is illuminated, replete with insights that transcend the confines of conventional treatment.

References

  1. National Cancer Institute. (2012). Vitamin E Intake and Mortality in Male Smokers. Retrieved from http://jnci.oxfordjournals.org/content/early/2012/07/12/jnci.djs277
  2. Onlinelibrary.wiley.com. (2012). Hepatology. Retrieved from
    http://onlinelibrary.wiley.com/doi/10.1002/hep.25762/full
Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

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LMU 69 – Fatherhood and Nutrition: A Hidden Influence on Offspring’s Health

LMU-69

LMU 69 – Fatherhood and Nutrition: A Hidden Influence on Offspring's Health

Source: Proceedings of Royal Society B. Biological Sciences Journal – 2017

Lifestyle Medicine Update (October 20, 2017)

Introduction: A Prelude to Paternal Nutrition

The journey to parenthood is a transformative one, intertwined with a tapestry of growth and development. While the importance of maternal nutrition during conception, pregnancy, and lactation is widely acknowledged, the role of paternal nutrition has lingered in the shadows. It’s a lesser-known facet, an enigma that researchers are beginning to unravel. In this narrative, we traverse the intricate landscape of paternal nutrition, exploring its profound impact on the growth and well-being of offspring during their formative months of life.

Maternal Nutrition: A Keystone for Fetal Development

The significance of maternal nutrition in shaping the trajectory of fetal growth and development is etched in scientific literature. Even marginal deficiencies in vital nutrients like folic acid, vitamin B12, and iron can cast a shadow on the offspring’s future. Neural tube defects like spina bifida lurk as potential risks, while compromised brain development looms as an ominous spectre. This realm underscores the critical nature of maternal nourishment during conception, pregnancy, and lactation, often echoing across the first 3-6 months of an infant’s life.

Beyond Maternal Nutrition: Paternal Influence Emerges

However, the canvas is far more complex. The focal point shifts to the nutritional status of the often-overlooked sperm donor – the father. Beyond the genetic legacy they contribute, fathers wield influence that extends beyond the confines of genes, a phenomenon christened as epigenetics. The scope of these influences transcends the bounds of mere genes, encompassing a spectrum of environmental effects. Toxins nestled within seminal plasma can be seamlessly passed to offspring, charting an unforeseen course for their health. Epigenetic impact also springs from factors like diet, obesity, and fitness, knitting a tapestry that can predispose offspring to conditions such as diabetes and heart disease.

Evidentiary Threads: Illuminating the Path

A poignant thread weaves through a Swedish study that illuminated the intricate link between early-life experiences and later generations’ health. This study unveiled a correlation between children who encountered ample food access at the age of 9 and higher rates of diabetes and heart disease among their grandchildren. In stark contrast, children grappling with mild to moderate food scarcity at a similar age witnessed their progeny’s resilience against heart disease and diabetes. This insight underscores the epigenetic echoes that food availability can orchestrate across generations, holding fathers as silent conductors of this symphony.

The Fruit Fly’s Whispers: An Unexpected Parallel

While the human story unfolds, an unexpected yet resonant parallel emerges from the realm of fruit flies. These diminutive creatures share a staggering 60 percent of human genes, and over 75 percent of our disease-related genes, rendering them an intriguing subject for scientific exploration. In a captivating experiment published in the Proceedings of the Royal Society B: Biological Sciences in 2017, researchers tinkered with the diet of male fruit flies, illuminating the echoes of paternal nutrition on offspring. The results were striking; male fruit flies consuming a diet rich in sugary carbohydrates but lacking in quality protein witnessed compromised offspring health and survival rates, particularly in subsequent mating rounds. This compelling experiment paints an intriguing parallel to the observations within human studies.

The Supplement Saga: Enhancing Sperm Potency

Amidst the broader tapestry of paternal nutrition lies the realm of supplements, offering a pathway to enhance sperm quality and motility. These supplements assume paramount importance for couples traversing the path of conception, especially when male sperm potency comes into question. Within this realm, a roster of supplements emerges as promising players:

  1. Vitamin C: This antioxidant emerges as a guardian, safeguarding sperm’s genetic material from damage and mutations. Vitamin C supplementation has showcased its potential in improving sperm quality, with smokers witnessing significant benefits. Even non-smokers experienced a staggering 140 percent increase in sperm counts within a week of consuming 1,000 mg of Vitamin C daily.
  2. Vitamin B12: Demonstrating its prowess, Vitamin B12 illuminated a path for men grappling with low sperm counts or motility. Doses ranging from 1,000 mcg to 6,000 mcg daily led to substantial improvements, painting a portrait of restored vitality.
  3. Vitamin E: With doses of 600-800 IU, Vitamin E embarks on a journey to bolster sperm quality and male fertility. Its role in diminishing free radical damage to sperm cells marks a vital contribution.
  4. L-Carnitine: In a realm where sperm motility takes center stage, L-Carnitine emerges as a promising protagonist. A daily dose of 1,000 mg sets the stage for enhanced motility and improved fertility.

Charting a Course for Future Generations

In a realm where paternal nutrition unfurls its wings, a symphony of influence comes to life. Studies collectively reinforce the notion that the nutritional status of fathers plays a pivotal role in shaping the health trajectory of future generations. Aspiring fathers are poised to tread the path of wellness, not just for themselves but for the generations they engender. The journey toward fatherhood beckons the cultivation of a healthier lifestyle, a conscious effort to forge a legacy of vitality.

References

  1. Michal Polak, Leigh W. Simmons, Joshua B. Benoit, Kari Ruohonen, Stephen J. Simpson, Samantha M. Solon-Biet. Nutritional geometry of paternal effects on embryo mortality. Proceedings of the Royal Society B: Biological Sciences, 2017; 284 (1864) http://rspb.royalsocietypublishing.org/content/284/1864/20171492
  2. Modern Nutrition in Health and Disease – 10th edition (2006). Editors: Shils M E, Shike M et al. Lippincott Wilkins & Wilkins.
Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

Adeeva Supplements