August 2023: Full Article


August 2023: Full Article

Women’s Hormonal Balance contains Black Cohosh, Soy Isoflavones and Gamma-Oryzanol, proven to alleviate menopausal symptoms.

Women’s Hormonal Balance contains three synergistic ingredients that help reduce menopausal symptoms, improve feelings of female well-being and promote health enhancement on many levels.

The Three Ingredients include:

  1. Black Cohosh (Standardized Grade)
  2. Soy Extract (Standardized to Isoflavone content)
  3. Gamma Oryzanol

Black Cohosh:

The 2021 review of Black Cohosh, in the journal Climacteric, confirms the findings of previous studies, showing that:

  • Black cohosh continues to be prescribed by medical doctors in many places around the world, as a safe and premiere treatment for menopausal symptoms (in Germany it is a prescription drug for menopause)
  • In 2011, and again in 2018, the European Medicines Agency issued an official monograph indicating a positive benefit–risk ratio for the use of Black cohosh in the treatment of menopausal symptoms, indicating that it is highly effective and side effects are rare and usually mild (GI upset, skin rash, headache).
  • The researchers reviewed 35 clinical studies and one meta-analysis comprising of 43,759 women, of which 13,096 were treated with a standardized grade of Black cohosh.
  • They showed that compared to placebo, women taking Black cohosh for menopausal symptom management had a significantly superior reduction in severity and frequency of a variety of menopausal symptoms, including some psychological symptoms.
  • They also showed that compared to low-dose estrogen replacement therapy, women using Black cohosh experienced equal symptomatic relief and had fewer side effects than the women using estrogen hormone replacement.
  • As they indicated, Black cohosh was better tolerated than low-dose estrogen therapy.

Main Reference:

Castelo-Branco C et al. Review & meta-analysis: isopropanolic black cohosh extract iCR for menopausal symptoms – an update on the evidence.                              Climacteric, 2021; 24 (2) https://www.tandfonline.com/doi/full/10.1080/13697137.2020.1820477

Other Supporting References:

National Institutes of Health (office of dietary supplements): Black Cohosh                                                                                                                    https://ods.od.nih.gov/factsheets/BlackCohosh-HealthProfessional/

Mehrpooya M et al. A comparative study on the effect of “black cohosh” and “evening primrose oil” on menopausal hot flashes. J Educ Health Promot. 2018, 7 (36)                https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868221/

Soy Isoflavones:

The 2016 review article on soy extract with isoflavones and treatment of menopausal symptoms and overall female well-being, in the journal Nutrients (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5188409/) highlighted the following findings:

  • Soy extract reduces hot flashes and other menopausal symptoms, lowers blood cholesterol, helps to reduce high blood pressure, improves blood
    flow through the heart arteries (coronary blood vessels) and provides other effects that reduce risk of cardiovascular disease – the number one killer of
    postmenopausal women in North America and in most developed countries.
  • Soy extract helps to support bone density, reducing osteoporosis risk, and the evidence is also strong to show that it decreases risk of breast cancer,
    as well as reducing the risk of breast cancer recurrence in breast cancer survivors.
  • It may also help to improve brain function (cognition) and reduce the risk of uterine cancer. And contrary to what many people have heard from
    pseudo-experts, soy consumption does not inhibit thyroid hormone production, secretion or function or predispose to an under active thyroid
    problem.
  • The 2017 review of Soy Isoflavones in Skin Health and Appearance (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490601/) showed that soy isoflavone supplementation can counter age-related skin changes caused by the decline in estrogen. Isoflavones stimulate collagen production, enhance skin DNA repair and have been shown to reverse fine lines and shallow wrinkles in double-blind placebo-controlled studies with women in their late 30’s and early 40’s.
  • Moreover, the 2022 review of Soy Isoflavones and Cancer (https://www.frontiersin.org/articles/10.3389/fnut.2022.847421/full) showed that the consumption of  25 mg of soy isoflavones daily is associated with an overall reduction in cancer risk of 10%.

Gamma-oryzanol (Ferulic acid):

A derivative of rice bran oil, studies continue to show that Gamma-oryzanol supplementation can reduce menopausal symptoms by up to 50% as a singular treatment. It can also help to reduce high cholesterol and triglycerides, and studies evaluating its anti-cancer properties are underway (https://www.sciencedirect.com/topics/medicine-and-dentistry/gamma-oryzanol?utm_source=newsletter&utm_medium=social&utm_campaign=medicine-and-dentistry).

Women’s Hormonal Balance combines the synergistic properties of Black cohosh, Soy Extract and Gamma-oryzanol into one potent menopause-treating formula for
female well-being.

This supplement can also be used to help manage PMS in younger women, as explained in Dr. Meschino’s webinar on this subject (complete with all scientific
references), which can be viewed at the following link:                                                                                                                                                                                                          https://adeeva.com/dr-meschinos-webinars-on-nutritional-medicine/

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