Introduction:

Soybeans contain isoflavones, including genistein and daidzein, which offer potential health advantages, from cancer prevention to cholesterol reduction.

Anti-Cancer and Cholesterol-Lowering Effects:

Isoflavones, particularly genistein, display anti-cancer properties and can help lower cholesterol, especially when replacing high-fat animal products in the diet.

Genistein’s Impact on Blood Sugar and Triglycerides:

A significant study published in Clinical Nutrition (August 2018) showcased genistein’s potential to enhance blood sugar regulation and reduce triglycerides in pre-diabetic patients with fatty liver (NASH).

Study Details and Results:

The double-blind clinical trial involved 82 subjects with pre-diabetes and NASH. Half took 250 mg of genistein supplement for 8 weeks, revealing improved blood sugar control, lowered triglyceride levels, reduced inflammation markers, and decreased oxidative stress.

Complementary Health Improvements:

Beyond blood sugar and triglyceride benefits, the genistein group also experienced reductions in belly fat and percentage body fat.

Natural Sources of Soy Isoflavones:

Regularly consuming soy-based foods (edamame, tofu, soy nuts, tempeh, etc.) can provide 50-75 mg of soy isoflavones daily. Replacing high-fat animal proteins with these options can improve cholesterol levels and reduce cancer risk.

Accumulative Benefits over Time:

Long-term consumption of soy isoflavones, including genistein, through dietary choices can offer accumulated health advantages by accumulating in key body tissues.

Considering Genistein Supplements:

If dealing with fatty liver, pre-diabetes, or type 2 diabetes, discussing the Clinical Nutrition study with a healthcare professional can help determine the potential benefits of incorporating a genistein supplement.

Conclusion: Leveraging Soy’s Power for Health Improvement

Soy, rich in genistein and isoflavones, presents a range of health benefits from combating cancer to enhancing blood sugar control and reducing triglycerides. Incorporating soy-based foods into the diet offers a natural way to reap these advantages, with the potential option of considering genistein supplements under medical guidance.

Reference:

Amant S, Effekharri MH et al. Genistein supplementation improves insulin resistance and inflammatory state in non-alcoholic fatty liver patients: A Randomized, controlled trial. Clinical Nutrition. 2018. 37;4:1210-1215.
https://www.clinicalnutritionjournal.com/article/S0261-5614(17)30202-9/fulltext

Eat Smart, Live Well, Look Great,

Dr. Meschino