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LMU – 184 Revitalizing with Hyperbaric Oxygen Therapy: Unlocking Anti-Aging Potential


LMU – 184 Revitalizing with Hyperbaric Oxygen Therapy: Unlocking Anti-Aging Potential

Source: Journal “Aging” (2020)

Lifestyle Medicine Update (Dec 4, 2020)


In the realm of medical innovation, hyperbaric oxygen therapy (HBOT) has emerged as a compelling approach, offering a unique blend of comfort and therapeutic promise. This treatment entails reclining in a sealed chamber, complete with expansive windows for scenic views and the luxury of watching TV or movies on a large screen. Inside this chamber, the air becomes saturated with pure oxygen—a striking contrast to the 21% oxygen content typically found in the air we breathe. But what makes HBOT truly intriguing is its ability to increase atmospheric pressure, sometimes up to 3 or 4 times the norm, depending on the specific health condition being addressed. The result is an hour-long journey that, when repeated over 40 to 60 sessions (often daily), can unleash remarkable therapeutic benefits.

In the Canadian province of Ontario, where this author resides, the government health plan extends coverage for HBOT to address 14 distinct health conditions with a proven track record of efficacy. Among these conditions are chronic anemia, chronic non-healing wounds, delayed radiation injury, gangrene, osteomyelitis, and thermal burns. Yet, researchers continually explore HBOT’s potential applications, seeking to harness its healing powers for a broader range of health concerns.

Unveiling the Anti-Aging Potential of HBOT

One of the foremost researchers in the field of hyperbaric oxygen therapy, Professor Shai Efrati of the Sackler School of Medicine, has paved the way for groundbreaking advancements. His work has not only transformed our understanding of HBOT but has also opened new doors in the realm of anti-aging.

In a groundbreaking 2020 study, published in the journal Aging, Dr. Efrati and his colleagues embarked on an ambitious quest to evaluate the impact of HBOT on aging. Their study involved 35 healthy individuals, all aged 64 or older, who underwent an intensive series of 60 hyperbaric sessions over a span of 90 days. Throughout the treatment journey, participants provided blood samples at key intervals—before, during, and after the series of HBOT sessions. These samples were then subjected to rigorous analysis, focusing on various immune cells present in the bloodstream.

The Astonishing Anti-Aging Discoveries

The study’s findings unveiled two profoundly significant anti-aging effects of hyperbaric oxygen therapy:

  1. Telomere Lengthening: Telomeres, protective caps at the ends of DNA strands, are known to shorten with age. This natural process leads to immune cells and other body cells becoming inactive, a phenomenon known as senescence. Lengthening telomeres can reverse the aging of these cells, enhancing their efficiency in combating viruses, bacteria, pathogens, and even emerging cancer cells. Telomere extension is considered a coveted achievement in the realm of anti-aging, and HBOT demonstrated the potential to lengthen telomeres by an astonishing 20-38% in specific types of immune cells. This groundbreaking discovery aligns with the quest for the “Holy Grail” of anti-aging biology.
  2. Reduction in Senescent Cells: Another striking revelation emerged with the reduction of senescent or inactive immune cells by 11-37% following the HBOT sessions. This signifies that participants emerged from the treatment with a greater number of active and functional immune cells—an essential boost for the immune system. The implications are significant, as the immune system typically experiences a noticeable decline after the age of 50-60, increasing the risk of cancer and making individuals more susceptible to life-threatening infections.

While certain dietary habits, lifestyle choices, and specific supplements have been shown to slow or reverse aspects of immune system decline, this new research illuminates the potential of HBOT as an additional tool for older individuals seeking to fortify their immunity. Though the prospect of HBOT being covered by healthcare plans for this purpose may remain distant due to the need for consecutive treatments, the time and expense involved, it nonetheless offers a proactive intervention for those dedicated to preserving vitality and health as they age.

Conclusion: Embracing the Power of Hyperbaric Oxygen Therapy

Hyperbaric oxygen therapy, once reserved for specific medical conditions, is transcending boundaries to reveal its anti-aging potential. The journey within the sealed chamber, saturated with pure oxygen and amplified pressure, is proving to be an intriguing avenue for reversing the effects of aging on immune cells. With telomere lengthening and a reduction in senescent cells, HBOT has carved a niche in the quest for a more youthful and robust immune system.

While the road to realizing the full potential of HBOT as an anti-aging tool may be marked by logistical and financial considerations, it stands as a testament to the ever-evolving landscape of health and wellness. As the pursuit of vitality and longevity continues, hyperbaric oxygen therapy emerges as an intriguing addition to the arsenal of anti-aging enthusiasts.


  1. Yafit Hachmo, Amir Hadanny, Ramzia Abu Hamed, Malka Daniel-Kotovsky, Merav Catalogna, Gregory Fishlev, Erez Lang, Nir Polak, Keren Doenyas, Mony Friedman, Yonatan Zemel, Yair Bechor, Shai Efrati. Hyperbaric oxygen therapy increases telomere length and decreases immunosenescence in isolated blood cells: a prospective trial. Aging, 2020. [Read more](
  2. ScienceDaily. (2020, November 20). Hyperbaric oxygen therapy increases longevity and prevents cognitive decline, Tel Aviv University study shows. [Read more](
  3. National Center for Biotechnology Information. (2019). Astragalus and Telomeres. [Read more](
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Dr. Meschino

Dr. James Meschino


Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

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