Source: Frontiers of Endocrinology Journal (2019)

Lifestyle Medicine Update (August 4, 2021)

Introduction:

Sleep is a vital component of a healthy life, and when it’s elusive, it can have cascading effects on our well-being. If you’re among the many who grapple with insomnia or disrupted sleep patterns, a 2019 research paper published in the journal Frontiers of Endocrinology and other groundbreaking studies offer intriguing insights into a natural remedy for sleep issues: melatonin. In this article, we’ll explore the role of melatonin in brain function, its potential to prevent brain degeneration, and why it’s becoming an increasingly preferred choice for managing sleep problems, especially for those over 55.

The Alarming Risks of Prescription Sleeping Medications

In today’s fast-paced world, sleep disorders are increasingly common, leading to a surge in the use of prescription sleeping medications. According to research, about 4% of all adults and 10% of those over 65 years of age in this country regularly take prescription sleeping medications to combat insomnia and sleep problems.

However, recent studies have raised red flags about the use of these medications. One alarming finding suggests that sleeping pills are associated with an increased risk of unsteadiness, leading to falls and fractures, especially in the elderly. In fact, research from Dalhousie University suggested that one-third of hip fractures in people aged 85 and older may be attributed to the use of these drugs. Moreover, the use of sleep medications is linked to a higher risk of pneumonia, memory problems, dependence, and withdrawal issues.

In 2012 and 2018, reports in medical journals revealed that individuals using prescription sleep medications faced significantly increased risks of cancer, premature death, serious infections, mood disorders, accidental injuries, suicides, and homicides compared to those who did not use these drugs.

Melatonin: A Natural Alternative

In contrast to the risks associated with prescription sleeping medications, melatonin is a natural agent that offers a safer and non-toxic solution for sleep problems. Melatonin has not only been shown to help individuals fall asleep more quickly but also to provide a deep, restorative sleep.

Beyond its role as a sleep aid, melatonin holds promise in preventing brain degeneration. Studies suggest that melatonin may help block the development of Alzheimer’s disease, Parkinson’s disease, and possibly Lou Gehrig’s disease. It also modulates immune function, helping to maintain or restore immunity as we age.

Recent research even indicates that melatonin can reverse mild cognitive impairment, which is often the first step toward dementia and Alzheimer’s disease. Additionally, melatonin acts as a potent brain antioxidant, protecting against free radical damage.

Melatonin’s Wider Health Benefits

Melatonin’s benefits extend beyond sleep and brain health. Studies suggest that it may help prevent breast and prostate cancer, along with other cancer types. In breast cancer patients undergoing medical treatment, melatonin has been used as an adjunct therapy. Furthermore, melatonin shows promise in reducing the progression of macular degeneration, a leading cause of blindness in individuals over 55, and in aiding those suffering from tinnitus, a condition characterized by ringing in the ears.

A Natural Blend for Restful Sleep and Brain Health

For those seeking an alternative to prescription sleep medications, a combination of melatonin, GABA, 5-HTP, and Bacopa monnieri may offer a wiser, safer, and more natural choice. GABA and 5-HTP work together to improve sleep quality and counteract caffeine-induced insomnia. Bacopa monnieri, a natural plant-based agent, helps protect the brain against free radical damage and other processes associated with dementia and Alzheimer’s disease. As we age, these nutrients become increasingly important for brain health and the prevention of brain degeneration.

In conclusion, melatonin is a natural ally for sound sleep and overall health. Its potential to improve sleep quality and protect against various neurodegenerative diseases makes it an attractive option for those seeking to address sleep issues while promoting long-term well-being.

References:

1. [2019 Update Melatonin and Neurodegeneration (Frontiers of Endocrinology)](https://www.frontiersin.org/articles/10.3389/fendo.2019.00480/full)
2. [Dalhousie University – Dal News](https://www.dal.ca/news/2021/01/25/researchers-takes-aim-at-highest-rates-of-sleeping-pill-reliance.html)
3. [BMJ Open – Risk of cancer in users of benzodiazepines and related drugs](https://bmjopen.bmj.com/content/2/1/e000850.full?sid=f0956753-511d-4e70-9230-c1e8aa5df0d3)
4. [Prescription Medications for Insomnia: A Review of Longitudinal Ambulatory Care Data – American Journal of Public Health](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890308/)
5. [Melatonin for the prevention and treatment of cancer – Oncotarget Journal](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503661/)
6. [Dietary Supplements and Nutraceuticals Under Investigation for Covid-19 Prevention and Treatment – National Institutes of Health Preprint Pilot](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872359/)
7. [Melatonin’s effects on immunity: A systematic review and meta-analysis](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946322/)
8. [Overview of melatonin and breast cancer](https://www.naturalmedicinejournal.com/journal/2010-02/overview-melatonin-and-breast-cancer)
9. [Melatonin for the prevention and treatment of cancer](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503661/)
10. [How to Optimize Sleep: The Sleep Foundation](https://www.sleepfoundation.org/sleep-hygiene/healthy-sleep-tips)
11. [Melatonin for the prevention and treatment of cancer](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503661/)
12. [Melatonin and Age-Related Macular Degeneration](https://www.hindawi.com/journals/ecam/2012/606424/)

Eat Smart, Live Well, Look Great,

Dr. Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.