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LMU 227 – Optimizing Cholesterol Levels Naturally: The Role of Gum Guggul

gumguggul

LMU-227 Optimizing Cholesterol Levels Naturally: The Role of Gum Guggul

Source: Cardiovascular Drug Reviews (2007)

Lifestyle Medicine Update (January 19, 2022)

Introduction:

Cholesterol management is a pivotal aspect of maintaining cardiovascular health. While reducing LDL-cholesterol (the “bad” cholesterol) is a common focus, raising HDL-cholesterol (the “good” cholesterol) is equally important. In a previous Lifestyle Medicine Update, we explored various dietary and lifestyle changes that can help lower LDL-cholesterol. However, strategies that lower LDL don’t always have the same effect on raising HDL. This article delves into the remarkable potential of Gum Guggul, a natural supplement, to elevate HDL levels effectively.

Balancing Cholesterol: More Than Just Lowering LDL

The importance of cholesterol management cannot be overstated. High LDL-cholesterol levels contribute to the accumulation of plaque in artery walls, increasing the risk of cardiovascular disease, heart attacks, and strokes. Reducing LDL-cholesterol through dietary and lifestyle changes is essential. Still, it’s equally crucial to focus on raising HDL-cholesterol, as HDL serves as a “clean-up crew” that helps remove cholesterol from artery walls, supporting overall heart health.

While some lifestyle modifications can moderately increase HDL, individual responses vary, often due to genetic factors. However, there are promising supplements that have shown the ability to raise HDL levels in clinical trials. In this article, we’ll explore Gum Guggul, a natural agent with a remarkable track record in HDL elevation.

The Power of Gum Guggul

Studies conducted in Asia and India have revealed that Gum Guggul supplementation can lower LDL-cholesterol in 70-80% of individuals with high total cholesterol and LDL levels. On average, it reduces LDL-cholesterol by approximately 30%, a significant improvement. While roughly 20-30% of individuals may not respond to Gum Guggul due to strong genetic factors, those who do experience a welcome bonus: an average increase in HDL of 4%. This means that for many individuals, Gum Guggul not only lowers LDL-cholesterol but also raises HDL-cholesterol, a crucial dual benefit.

How Gum Guggul Works

The active ingredient in Gum Guggul, known as Guggulsterone, plays a pivotal role in cholesterol management. Guggulsterone prompts the liver to clear more LDL-cholesterol from the bloodstream. Once inside liver cells, it stimulates the conversion of LDL-cholesterol into bile acids, which are subsequently excreted through the bile duct into the intestine. From there, the body eliminates it with each bowel movement. This process effectively reduces circulating LDL-cholesterol levels.

Additionally, Gum Guggul encourages liver cells to synthesize more HDL-cholesterol, releasing it into the bloodstream. HDL then removes cholesterol from artery walls, returning it to the liver, where it can also be converted into bile acids and excreted from the body. This dual action makes Gum Guggul a potent addition to any cholesterol management strategy.

Other Benefits of Gum Guggul

Beyond its cholesterol-modifying effects, Gum Guggul offers additional health benefits. It provides anti-inflammatory effects, which can be advantageous for cardiovascular and joint health. This resin, derived from the Mukul myrrh tree in India, has demonstrated its potential to enhance overall well-being.

Side Effects and Considerations

One notable side effect of Gum Guggul is a skin rash, affecting approximately 9% of users, typically occurring within the first week to 10 days of use. Unfortunately, there is no reliable way to predict who might experience this side effect. However, discontinuing Gum Guggul resolves the rash promptly.

Comprehensive Cholesterol Management: Gum Guggul and Artichoke Leaf Extract

For a synergistic approach to improving cholesterol levels, combining Gum Guggul with Artichoke Leaf Extract can be highly effective. In the next Lifestyle Medicine Update, we will explore the benefits of Artichoke Leaf Extract in detail.

Optimal Dosage and Conclusion

To harness the cholesterol-modifying power of Gum Guggul, an effective therapeutic dosage is 3 grams per day, typically in a supplement standardized to 2.5% guggulsterone content. Incorporating Gum Guggul into your cholesterol management routine can provide a natural and effective way to lower LDL and raise HDL for many individuals.

In conclusion, Gum Guggul has emerged as a valuable tool for optimizing cholesterol levels. While lowering LDL-cholesterol is essential, raising HDL-cholesterol plays a crucial role in overall cardiovascular health. With its dual action and additional benefits, Gum Guggul is a natural choice for those seeking comprehensive cholesterol management.

Reference:

Deng R. Therapeutic effects of gum guggul and its constituent guggulsterone: cardiovascular benefits. Cardiovascular Drug Reviews. 2007;25(4):375-390. [Link](https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1527-3466.2007.00023.x)

 

Eat Smart, Live Well, Look Great,

Dr. Meschino

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Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

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