Since the early 2000s, a humble fungus named Lion’s Mane mushroom, scientifically known as Hericium erinaceus, has been weaving its magic in the realm of memory enhancement. This captivating tale unfolds through studies revealing the mushroom’s ability to stimulate the
production of Nerve Growth Factor (NGF) and brain-derived neurotrophic factor (BDNF), promising hope for healing certain neuropathies and combating memory loss.

The Human Canvas: A 2009 Cognitive Symphony

In a mesmerizing 2009 study, individuals aged 50-80, grappling with mild cognitive impairment, experienced a cognitive symphony. Half of the participants indulged in the enchanting melody of Lion’s Mane mushroom supplementation, while the others danced to a placebo tune. Those consuming Lion’s Mane showcased a significant improvement in cognitive function scores, painting a vivid picture of the mushroom’s potential
to enhance mental clarity.

Animal Adventures: Lion’s Mane and the Alzheimer’s Quest

Embarking on animal adventures, researchers uncovered the mushroom’s prowess in slowing beta-amyloid plaque production—a key player in Alzheimer’s disease. Lion’s Mane emerged as a guardian, shielding brain cells against damage induced by cerebral artery occlusion. In mice with age-related cognitive decline, the mushroom performed a memory waltz, enhancing recognition memory by promoting nerve cell generation
in the hippocampus, the orchestrator of memory conversion from short-term to long-term.

Illuminating 2023: Lion’s Mane and the Neurochemistry Expedition

In the dawn of 2023, scientists from the University of Queensland embarked on a neurochemistry expedition. Their quest unveiled two active compounds in Lion’s Mane—Hericene A and polysaccharides—that not only traversed the blood-brain barrier but also orchestrated a symphony of nerve growth and memory boost in mice. The revelation marked a significant milestone, attributing the active constituent Hericene A as the enchanting catalyst behind improved memory and neurotrophic magic.

Your Journey with Lion’s Mane: A Symphony of Health

As the curtain rises on the magical properties of Lion’s Mane, incorporating it into your daily routine becomes a captivating prospect. The mushroom’s inclusion in medicinal blends, alongside reishi, shiitake, cordyceps, turkey tail, and others, becomes a harmonious choice. Beyond the age of 45-50, when the body’s immune system starts to wane, these mushroom blends become not only immune-modulators but also potential supporters of memory function.

Wisdom Beyond 55: A Memory Support Supplement

In the grand ballad of life, the age of 55 ushers in the wisdom of memory support supplements. A daily dose featuring CDP-choline, Huperzine A, Phosphatidylserine, and Bacopa monnieri becomes the orchestral finale, weaving a tapestry of memory preservation.

Conclusion: The Symphony Continues

As we embrace the enchanting story of Lion’s Mane, let the mushroom’s symphony resonate in your journey toward vibrant health. With each sip of a mushroom blend or a memory support supplement, you become a part of the captivating melody, unlocking the secrets of memory preservation and embracing the magic within Lion’s Mane.

References:

1. Martinez-Marmol R et al. [Hericerin derivatives activate a pan-neurotrophic pathway in central hippocampal neurons converging
   to ERK1/2 signaling enhancing spatial memory.](https://pubmed.ncbi.nlm.nih.gov/36660878/) J Neurochemistry. January 20, 2023.
2. Active compound in Lion’s Mane mushroom improves nerve growth and memory. [News Medical Life Sciences. Feb 13, 2023.](https://www.news-medical.net/news/20230213/Active-compound-in-Lione28099s-Mane-mushroom-improves-nerve-growth-and-memory.aspx#:~:text=In%20a%20recent%20study%20published,nerve%20growth%20and%20boost%20memory)
3. Tsai-Teng T, et al. [Erinacine A-enriched Hericium erinaceus mycelium ameliorates Alzheimer’s disease-related pathologies in
   APPswe/PS1dE9 transgenic mice.](https://pubmed.ncbi.nlm.nih.gov/27350344/) J Biomed Sci. 2016; 23 (1): 49.
4. Mori K et al. [Improving effects of the mushroom Yamabushitaki (Hericium erinaceus) on mild cognitive impairments: a double-blind placebo-controlled clinical trial.](https://pubmed.ncbi.nlm.nih.gov/18844328/) Phytother Res. 2009; 23 (3): 367-72.
5. Ratto D et al. [Hericium erinaceus improves recognition memory and induces hippocampal and cerebellar neurogenesis in frail mice during aging.](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521003/) Nutrients. 2019; 11 (4): 715.

Dr. Meschino