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LMU 54 – Omega-3 Fats: A Promising Shield Against Alzheimer’s Disease

Higher Omega-3 Fat Status Linked To Better Brain Blood Flow

LMU 54 – Omega-3 Fats: A Promising Shield Against Alzheimer's Disease

Source: Journal of Alzheimer’s Disease (May 19, 2017)

Lifestyle Medicine Update (May 27, 2017)


Emerging from the pages of the Journal of Alzheimer’s Disease on May 19, 2017, is a research study that casts a new light on the protective potential of omega-3 fats against the menacing threat of Alzheimer’s disease. This study, in harmony with a growing body of evidence, underscores the instrumental role played by omega-3 fats in mitigating the risk of Alzheimer’s disease. Moreover, it unravels a novel dimension by illuminating the connection between higher omega-3 fat status, enhanced blood flow to vital brain regions, and cognitive prowess—key components in the fight against age-related memory loss.

Omega-3 Fats: Guardians of Cognitive Health

The pivotal link between omega-3 fats and Alzheimer’s disease takes center stage as the research study unfolds. Individuals boasting higher omega-3 fat status emerge as beneficiaries of an added layer of protection against the onset of Alzheimer’s disease. This critical shield extends to the realm of cerebral blood flow, essential for mental acuity, learning, and memory preservation. The intricate interplay between omega-3 fats and cognitive vitality finds validation through comprehensive computerized neurocognitive testing, which demonstrated superior mental performance among those with elevated omega-3 fat levels.

Delving into the Study

The study, a convergence of expertise from a psychiatric referral clinic, enlisted 166 patients whose omega-3 fat status had been meticulously assessed. What unfolds is a resounding affirmation of the advantages associated with high omega-3 fat status. A compelling alliance emerges between robust omega-3 fat levels and improved blood flow, a phenomenon primed to fortify critical brain regions. These regions, integral for learning, memory retention, and the deterrence of depression and dementia, gain a new layer of resilience against age-related deterioration.

SPECT Scan: An Insightful Glimpse into Brain Dynamics

This research study is endowed with a novel dimension, as it harnesses the power of SPECT (Single Photon Emission Computed Tomography) scan technology. With unparalleled accuracy, SPECT scans illuminate the intricate web of blood flow within 128 distinct brain regions. The revelation of heightened blood flow prompted by optimal omega-3 fat status forms an invaluable addition to the arsenal of knowledge in the battle against Alzheimer’s disease. The alignment of omega-3 fats with the prevention of Alzheimer’s disease milestones such as beta-amyloid plaque and neurofibrillary tangles stands as a testament to their potential.

Omega-3 Fats: A Beacon of Prevention

The omega-3 fats, namely EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), have attracted considerable attention for their prowess in Alzheimer’s disease prevention. Informed by the collective insights from human observational studies and animal experimentation, the correlation between optimal omega-3 fat status and the prevention of Alzheimer’s disease hallmarks—beta-amyloid plaque and neurofibrillary tangles—shines through. Additionally, omega-3 fats excel in curbing brain inflammation, a factor pivotal in cognitive health. The study’s revelation of omega-3 fats’ capacity to enhance blood flow to critical brain domains and amplify cognitive performance unveils yet another facet of their multifaceted benefits.

Insights from Lead Author: Daniel G. Amen, MD

Daniel G. Amen, MD, the lead author, injects valuable perspective into the study’s findings. Dr. Amen aptly summarizes the study’s essence, underscoring the correlation between diminished omega-3 fatty acid levels and compromised blood flow to brain regions essential for cognition, learning, memory, depression deterrence, and defence against dementia.

Quantifying Omega-3 Fat Intake: A Blueprint for Prevention

An imperative question surfaces: how much omega-3 fat intake is requisite for Alzheimer’s disease prevention? The answer crystallizes around an approximate daily intake of 400 mg of omega-3 fat, primarily EPA and DHA. Translating this requirement into tangible practice, a 1000 mg fish oil capsule standardized to 30% EPA and 20% DHA provides an invaluable contribution of 500 mg of these pivotal omega-3 fats.

Conclusion: Illuminating a Path to Cognitive Resilience

The research study stands as a beacon of hope in the realm of Alzheimer’s disease prevention, offering a new perspective on the protective abilities of omega-3 fats. The link between omega-3 fats, enhanced blood flow, and cognitive performance adds a new dimension to the ongoing battle against age-related memory loss. Armed with the insights of this study, individuals are empowered to embrace omega-3 fats as allies in their quest to safeguard cognitive vitality and preserve the brilliance of the human mind.


  1. Journal of Alzheimer’s Disease May 19, 2017,

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Dr. Meschino

Dr. James Meschino


Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

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