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LMU 21 – Supplements Proven to Enhance Efficacy of Antidepressant Medication

LMU-21

LMU 21 – Supplements Proven to Enhance Efficacy of Antidepressant Medication

Source: The American Journal of Psychiatry (June, 2016)

Lifestyle Medicine Update (August 23, 2016)

If you’ve ever suffered from depression or know someone who has, you’ll want to know about a study published in June, 2016, in The American Journal of Psychiatry. In recent years, a number of clinical trials have shown that taking certain supplements in conjunction with antidepressant drugs can actually enhance their efficacy and improve outcomes for patients suffering from depression.

This means, adding specific supplements to an antidepressant medicine regime has been shown to speed up recovery time, improve responses in patients who were not previously responding to medication, or provide a more complete recovery and/or reduced relapse rate. This is important because overall, just 30-40% of patients with major depression have only a partial response to the use of antidepressant drugs and psychotherapy treatment – when you factor in relapse rates.

In a combined effort, researchers from the University of Melbourne, and researchers from Harvard University, examined 40 clinical human trials worldwide, alongside a systematic review of the evidence, examining the use of supplements as an adjunct to the treatment of depression. After reviewing all the worldwide studies performed up to December, 2015, they published their findings in the June, 2016 issue of The American Journal of Psychiatry. What they publisehd was the discovery that current research supports the addition of certain supplements to antidepressant medication management of depression, as it can increase the effectiveness of antidepressants for people with clinical depression.

This was especially true for 4 specific supplements, including:

  1. Omega-3 fats from fish oil
  2. SAMe (S-adenosylmethionine)
  3. Methylfolate (a form of the B-vitamin folic acid)
  4. Vitamin D

Each of these supplements boost the effectiveness of antidepressant medication.The strongest evidence was for Omega-3 fats from fish oil. The brain requires Omega-3 fats to improve what’s known as brain fluidity. With improved brain fluidity, the receptors on brain cells can more easily receive signals from the “feel good” brain chemicals, like serotonin, dopamine and norepinephrine. Antidepressant drugs help the brain increase levels of these mood-enhancing chemicals but brain cells need to have sufficient fluidity for their receptors (or “antennae”) to receive the message from the mood-enhancers. If the brain hardens, which can result from eating too much saturated fat or trans-fats, or insufficient omega-3 fats, then the brain cell receptor system is much less effective.

So, Omega-3 fats have been shown to improve the effectiveness of antidepressant drugs by improving brain fluidity. Omega 3 fat supplementation also:

  • decreases brain inflammation,
  • improves blood flow through the brain’s blood vessel network,
  • and may help improve nerve conduction or electrical transmission (communication) between nerve cells.

Some studies also show that it may help block the build up of beta-amyloid plaque – a hallmark feature of Alzheimer’s disease. A number of studies suggest that a higher intake of Omega-3 fats help to reduce risk of Alzheimer’s disease.

For all these reasons, Omega-3 fat supplementation from fish oil is a supplement to strongly consider.

The supplements SAMe and Methylfolate work by helping the brain synthesize more of mood-enhancing chemicals like serotonin, dopamine and noradrenaline. Antidepressant drugs slow the breakdown of mood-enhancing drugs, but only certain supplements like SAMe and Methylfolate can actually help the brain synthesize more mood-enhancing chemicals.

As for Vitamin D, studies show that Vitamin D is required to help the brain make serotonin, which is the ultimate feel good brain chemical or neurotransmitter.

My point is, many doctors don’t read The American Journal of Psychiatry every month, and therefore may not see this ground-breaking review paper. If you suffer from depression, or have suffered from depression, you may want to forward a link to this research article to your doctor. Or, you may want to provide the link to a friend of family member who suffers from depression, so they can forward it to their doctor. Hopefully, your doctor, or their doctor, will review the evidence and recommend an established daily dosage of one or more of the supplements highlighted in this review as a means to increase the effectiveness of the prescribed antidepressant medication.

I’ve attached a link to the research article and review in the text below.

References:

1. Sarris, J., Murphy, J., Mischoulon, D., Papakostas, G.I., Fava, M., et al. Adjunctive Nutraceuticals for Depression: A systematic review and meta-analysis. American Journal of Psychiatry, 2016, Vol. 173, issue 6, pp: 575-587.http://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.2016.15091228

2. https://www.sciencedaily.com/releases/2016/04/160426091725.htm


Eat Smart, Live Well, Look Great,

Dr. Meschino

If you’ve ever suffered from depression or know someone who has, you’ll want to know about a study published in June, 2016, in The American Journal of Psychiatry. In recent years, a number of clinical trials have shown that taking certain supplements in conjunction with antidepressant drugs can actually enhance their efficacy and improve outcomes for patients suffering from depression.

This means, adding specific supplements to an antidepressant medicine regime has been shown to speed up recovery time, improve responses in patients who were not previously responding to medication, or provide a more complete recovery and/or reduced relapse rate. This is important because overall, just 30-40% of patients with major depression have only a partial response to the use of antidepressant drugs and psychotherapy treatment – when you factor in relapse rates.

In a combined effort, researchers from the University of Melbourne, and researchers from Harvard University, examined 40 clinical human trials worldwide, alongside a systematic review of the evidence, examining the use of supplements as an adjunct to the treatment of depression. After reviewing all the worldwide studies performed up to December, 2015, they published their findings in the June, 2016 issue of The American Journal of Psychiatry. What they publisehd was the discovery that current research supports the addition of certain supplements to antidepressant medication management of depression, as it can increase the effectiveness of antidepressants for people with clinical depression.

This was especially true for 4 specific supplements, including:

  1. Omega-3 fats from fish oil
  2. SAMe (S-adenosylmethionine)
  3. Methylfolate (a form of the B-vitamin folic acid)
  4. Vitamin D

Each of these supplements boost the effectiveness of antidepressant medication.The strongest evidence was for Omega-3 fats from fish oil. The brain requires Omega-3 fats to improve what’s known as brain fluidity. With improved brain fluidity, the receptors on brain cells can more easily receive signals from the “feel good” brain chemicals, like serotonin, dopamine and norepinephrine. Antidepressant drugs help the brain increase levels of these mood-enhancing chemicals but brain cells need to have sufficient fluidity for their receptors (or “antennae”) to receive the message from the mood-enhancers. If the brain hardens, which can result from eating too much saturated fat or trans-fats, or insufficient omega-3 fats, then the brain cell receptor system is much less effective.

So, Omega-3 fats have been shown to improve the effectiveness of antidepressant drugs by improving brain fluidity. Omega-3 fat supplementation also:

  • decreases brain inflammation,
  • improves blood flow through the brain’s blood vessel network,
  • and may help improve nerve conduction or electrical transmission (communication) between nerve cells.

Some studies also show that it may help block the build up of beta-amyloid plaque – a hallmark feature of Alzheimer’s disease. A number of studies suggest that a higher intake of Omega-3 fats help to reduce risk of Alzheimer’s disease.

For all these reasons, Omega-3 fat supplementation from fish oil is a supplement to strongly consider.

The supplements SAMe and Methylfolate work by helping the brain synthesize more of mood-enhancing chemicals  like serotonin, dopamine and noradrenaline. Antidepressant drugs slow the breakdown of mood-enhancing drugs, but only certain supplements like SAMe and Methylfolate can actually help the brain synthesize more mood-enhancing chemicals.

As for Vitamin D, studies show that Vitamin D is required to help the brain make serotonin, which is the ultimate feel good brain chemical or neurotransmitter.

My point is, many doctors don’t read The American Journal of Psychiatry every month, and therefore may not see this ground-breaking review paper. If you suffer from depression, or have suffered from depression, you may want to forward a link to this research article to your doctor. Or, you may want to provide the link to a friend of family member who suffers from depression, so they can forward it to their doctor. Hopefully, your doctor, or their doctor, will review the evidence and recommend an established daily dosage of one or more of the supplements highlighted in this review as a means to increase the effectiveness of the prescribed antidepressant medication.

I’ve attached a link to the research article and review in the text below.

References:

1. Sarris, J., Murphy, J., Mischoulon, D., Papakostas, G.I., Fava, M., et al. Adjunctive Nutraceuticals for Depression: A systematic review and meta-analysis. American Journal of Psychiatry, 2016, Vol. 173, issue 6, pp: 575-587.http://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.2016.15091228

2. https://www.sciencedaily.com/releases/2016/04/160426091725.htm

Eat Smart, Live Well, Look Great

Dr. Meschino

Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

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LMU 20 – The Impact of Caffeine on Sleep, Alertness, and Performance

LMU-20

LMU 20 – The Impact of Caffeine on Sleep, Alertness, and Performance

Source: Journal Nutrition Reviews 2014

Lifestyle Medicine Update (August 19, 2016)

Introduction:

Caffeine, a widely consumed stimulant found in coffee, tea, and other beverages, has long been associated with various effects on the body, including insomnia, increased alertness, and enhanced athletic performance. But how exactly does caffeine work, and can it genuinely improve alertness and performance in a sleep-deprived state? A comprehensive review paper published in “Nutrition Reviews” in 2014 delves into the science behind caffeine’s effects and potential benefits and risks.

Caffeine’s Mechanism of Action

Caffeine exerts its effects by blocking adenosine receptors, preventing them from receiving signals from the molecule adenosine. As a result, caffeine triggers the release of several chemicals in the body, including adrenaline, dopamine, and acetylcholine. These chemical releases increase alertness, elevated blood pressure, heart rate, and a heightened pleasure-reward system mediated by dopamine.

Sleep and Alertness Regulation

The brain tracks sleep in two primary ways: the duration of wakefulness on a given day and the cumulative rest over several days. When cumulative sleep is compromised, the brain accumulates a “sleep debt” that needs to be repaid at some point. Similarly, staying awake for an extended period increases sleep debt. Caffeine has been shown to temporarily help overcome sleepiness in such sleep-deprived states by improving the ability to stay awake, preventing slowed reaction times, and reducing lapses of attention.

Dosage and Effects

The effects of caffeine are dose-dependent, meaning that performance improves as caffeine intake increases, up to around 600 mg. A typical cup of coffee contains 150-200 mg of caffeine, while decaffeinated coffee has only 2-12 mg. However, side effects like jitteriness, abdominal pain, and nausea become more common as the dose increases.

Caffeine Timing and Circadian Rhythms

Studies have shown that caffeine intake in the morning, afternoon, and overnight can counteract the body’s circadian-related performance decrements, boosting alertness and improving neurobehavioral functioning compared to a placebo. However, suppose one continues to deprive themselves of adequate sleep. In that case, caffeine ingestion will have little effect in preventing performance deficits and mini-sleep attacks, which can be hazardous, especially during activities like driving or operating heavy machinery.

Caffeine as a Substitute for Sleep

While caffeine can temporarily boost performance, it is not a replacement for sufficient, healthy sleep. Relying on caffeine to sustain alertness throughout the day and work through the night can lead to severe consequences, especially for those with heart conditions, high blood pressure, diabetes, or intestinal diseases. People who do not metabolize caffeine efficiently may also face an increased risk of heart attacks, mainly middle-aged men.

The Importance of Adequate Sleep

Most adults require 7-8.5 hours of habitual sleep within a 24-hour cycle. However, over 28% of Americans sleep less than 7 hours per night on average. While some individuals can function with 5-6 hours of sleep, they are the exception rather than the norm. Accumulating sleep debt and consistently using caffeine as a substitute for rest can lead to decreased alertness and performance, impaired decision-making, and difficulties in achieving wellness goals, such as maintaining a healthy weight.

The Bottom Line

For optimal health, it is essential to prioritize adequate sleep, and caffeine should only be used occasionally to give a temporary performance boost. Relying on caffeine to compensate for inadequate sleep is not a sustainable solution and may have adverse health effects. In the next Lifestyle Medicine Update, further aspects of caffeine, such as its metabolism in the body and potential disease-preventing properties, will be explored.

Reference:

Spaeth AM, Goel N, Dinges DF. Cumulative neurobehavioral and physiological effects of chronic caffeine intake: Individual differences and implications for using caffeinated energy products. Nutrition Reviews. 2014. Vol 72 (s1): 34-47

http://onlinelibrary.wiley.com/doi/10.1111/nure.12151/abstract

Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

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LMU 19 – Coenzyme Q10: A Vital Nutrient for Heart Health and Beyond

LMU-19

LMU 19 – Coenzyme Q10: A Vital Nutrient for Heart Health and Beyond

Source: Journal Nurse Prescribing (2013)

Lifestyle Medicine Update August 14, 2016

Introduction:

Coenzyme Q10, commonly known as CoQ10, plays a pivotal role as a vitamin-like substance produced naturally within the human body. It is essential for converting food into energy in almost all cells. Unfortunately, as we age, our bodies natural production of CoQ10 declines. By the time we reach our 50s, this reduction in CoQ10 levels can contribute to the development of various health disorders. This article aims to shed light on the significance of CoQ10 in maintaining optimal health, particularly for the heart and explores its potential benefits in various health conditions.

The Heart-Muscle Connection

One critical aspect of CoQ10’s function is its impact on the heart muscle. As CoQ10 levels decline, our cells become less efficient in producing the necessary energy to maintain their function. This deficiency is particularly significant for the heart, which requires substantial energy to perform its continuous pumping action. Consequently, the heart muscle may gradually weaken, potentially leading to congestive heart failure as we age. Congestive heart failure is the leading cause of hospital admissions for people over 65.

However, research has shown that CoQ10 supplementation can reverse this condition and significantly improve cardiac function and quality of life in congestive heart failure patients. CoQ10 has been an approved treatment for congestive heart failure in Japan since the 1970s, underscoring its effectiveness in restoring heart muscle function. Analogous to inserting a missing piston back into a car’s engine, CoQ10 replenishment allows the heart muscle to pump optimally again, providing more strength and efficiency.

Lowering Blood Pressure and Reducing Plaque Build-Up

Beyond its impact on the heart muscle, CoQ10 supplementation has demonstrated benefits in reducing high blood pressure. Studies have shown that it can lower systolic blood pressure by an average of 17 points and diastolic pressure by 10. This effect is attributed to CoQ10’s ability to stimulate the release of nitric oxide in the artery walls, which promotes artery relaxation and improved blood circulation with reduced resistance.

Furthermore, CoQ10 acts as an antioxidant, preventing free radical damage to cholesterol in the bloodstream. By reducing plaque build-up in the artery walls, CoQ10 decreases the risk of heart attacks and ischemic strokes.

Managing Cholesterol-Lowering Statin Drugs Side Effects

CoQ10 supplementation has also been associated with reducing muscle pain, a common side effect of cholesterol-lowering statin drugs. Statin drugs block CoQ10 synthesis in the body, leading to potential CoQ10 depletion and increasing the risk of muscle damage and congestive heart failure. By taking CoQ10 supplements with statins, patients can help prevent these adverse effects and maintain their CoQ10 levels.

Wider Health Implications

Beyond cardiovascular health, CoQ10 has demonstrated potential benefits in managing Parkinson’s disease, fibromyalgia, migraines, and male infertility problems. Various clinical trials and studies support CoQ10’s positive role in preventing and managing cardiovascular disease. None of these studies have reported significant adverse effects following oral supplementation with CoQ10.

Optimizing CoQ10 Intake

For general health optimization, it is recommended that individuals over the age of 45 take at least 30 mg of CoQ10 daily, while those over 60 increase their daily dose to 60 mg. Most authorities suggest a daily intake of 90-100 mg for patients taking cholesterol-lowering statins to maintain CoQ10 levels in the body.

Patients with specific health conditions, such as congestive heart failure, high blood pressure, Parkinson’s disease, and fibromyalgia, may require therapeutic doses of CoQ10. In such cases, it is essential to incorporate CoQ10 into the overall medical management under the supervision of attending physicians.

Conclusion

In conclusion, Coenzyme Q10, or CoQ10, is a critical nutrient for maintaining energy production in almost all body cells. Its significance in heart health is particularly noteworthy, as it can help prevent and manage congestive heart failure, lower blood pressure, and reduce plaque build-up in arteries. Additionally, CoQ10 supplementation may alleviate muscle pain caused by cholesterol-lowering statin drugs.

This vitamin-like substance has shown promise in various other health conditions and is the subject of numerous peer-reviewed medical articles. Given the extensive research supporting its benefits and the absence of significant adverse effects, CoQ10 is a promising aid in preventing and managing cardiovascular diseases.

To delve deeper into CoQ10, you can access the research paper linked below for a comprehensive review of its applications and benefits.

Reference:

Mantle D. Pharmacology of coenzyme Q10: Relevance to cardiovascular and other disorders. Nurse Prescribing. 2013; 11(12):602-607. http://www.magonlinelibrary.com/doi/abs/10.12968

Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

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LMU 18 – Alcohol and Cancer Risk: A Comprehensive Review for Public Health

LMU-18

LMU 18 – Alcohol and Cancer Risk: A Comprehensive Review for Public Health

Source: Journal Addiction, July 21, 2016

Lifestyle Medicine Update (August 7, 2016)

Introduction:

Alcohol consumption has been a part of human culture for centuries, but scientific evidence has brought to light its link to cancer risk in recent years. This article aims to examine the association between alcohol consumption and cancer development thoroughly. The 2016 research review published in the journal “Addiction” was pivotal in understanding the extent of the risks. This comprehensive review will discuss the findings from that study and other relevant research to emphasize the wake-up call for public health and the need for awareness campaigns to address this significant issue.

The Association between Alcohol and Cancer

The study published in “Addiction” shed light on the undeniable relationship between alcohol consumption and cancer risk. It revealed that even light to moderate drinking can increase the likelihood of developing seven primary cancers: oropharynx, larynx, esophagus, liver, colon, rectum, and female breast. Surprisingly, the type of alcoholic beverage did not alter the risks; the dangers were equally present for hard liquor, beer, wine, and other spirits.

Debunking Myths: Red Wine and Cardiovascular Benefits

One of the prevailing myths is that red wine offers protective benefits for the heart. However, the evidence does not support this claim. Public health organizations like the UK and New Zealand medical associations, the Cancer Society, and National Heart Foundation have adopted evidence-based position statements to dispel such notions and emphasize alcohol’s carcinogenicity.

Global Impact of Alcohol on Cancer Mortality

From a global perspective, alcohol contributed to approximately half a million cancer-related deaths in 2012, accounting for 5.8% of all cancer deaths worldwide. The heaviest drinkers face the highest risks, but even low to moderate alcohol consumption significantly burdens public health systems. The impact on women’s health is especially concerning, with studies showing increased risks of breast cancer associated with alcohol consumption.

Reversible Risks: The Path to Abstinence

Despite the alarming risks, there is hope in reducing cancer risks. The study found that individuals who ceased drinking experienced a decline in cancer risks over time. For example, the risk of laryngeal and pharyngeal cancers decreased by approximately 15% within five years of quitting, and the risk of primary liver cancer reduced by 6-7% per year of non-drinking. After over two decades of abstinence, the chances for these cancers eventually matched those of never-drinkers.

Beyond the Seven Prime Tissue Sites: Other Susceptible Organs

While the seven prime tissue sites have been thoroughly studied, emerging research suggests alcohol’s causal contribution to cancer in other areas, including the pancreas, prostate, and skin (melanoma). Heavy drinking occasions and average consumption have also been associated with an increased risk of pancreatic cancer.

Empowering Individuals to Make Healthier Choices

The findings from various studies highlight the critical role of public awareness campaigns in combating alcohol-related cancer risks. Educating the public about the dangers of alcohol consumption and debunking myths surrounding its potential benefits is essential. Empowering individuals to make informed decisions and adopt healthier lifestyles can significantly reduce cancer risk.

Recommendations for Reducing Cancer Risk

Reducing alcohol consumption is a critical factor in mitigating cancer risk. For those who choose to drink, limiting intake to 1-2 drinks per week can help minimize the dangers. Additionally, adopting prudent dietary practices, maintaining ideal body weight, engaging in regular physical activity, and avoiding exposure to other carcinogens are vital steps in further reducing cancer risk.

Conclusion

In conclusion, the relationship between alcohol consumption and cancer risk is unequivocal. The 2016 study published in “Addiction” served as a wake-up call for public health, highlighting the undeniable link between alcohol and several types of cancer. Debunking myths surrounding red wine’s protective benefits and cardiovascular advantages is crucial in shaping public perception. Empowering individuals to make informed decisions, along with the adoption of healthier lifestyle choices, can lead to a substantial reduction in cancer-related morbidity and mortality.

As we move forward, collective efforts are needed to promote public health, spread awareness about alcohol’s impact on cancer risk, and implement strategies that support individuals in making healthier choices. We can work towards a healthier and cancer-resistant society through such collaborative initiatives.

References:

  1. Shield KD et al. (2016). Global burden of diseases, injuries, and risk factors for young people’s health during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. The Lancet, 387(10036), 2383–2401.
  2. Connor J. (2017). Alcohol consumption as a cause of cancer. Addiction, 112(2), 222–228.
  3. Medscape – Interview-Statement:                                                                                                        http://www.medscape.com/viewarticle/866727nlid=108668_1842&src=WNL_mdplsfeat_160802_mscpedit_wir&uac=62515BJ&spon=1
  4. Million Women Study Collaborators. (2009). Alcohol and cancer risk: a prospective study. International Journal of Cancer, 125(3), 647–654.
  5. Bagnardi V, et al. (2015). Alcohol consumption and site-specific cancer risk: a comprehensive dose-response meta-analysis. British Journal of Cancer, 112(3), 580–593.
Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

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LMU 17 – Lifestyle Change Shown to Reverse Aging of our Cells

LMU-17

LMU 17 – Lifestyle Change Shown to Reverse Aging of our Cells

Source: The Lancet, 2013

Lifestyle Medicine Update (July 30, 2016)

Introduction:

In 2013, a groundbreaking study published in Lancet shook the scientific community by revealing that fundamental lifestyle changes could reverse cellular aging by lengthening telomeres—the protective caps at the end of our DNA strands. Telomeres play a crucial role in cell replication, as they shorten with each cycle. When they reach a critical length, cells can malfunction, leading to various health issues, including cancer and rapid aging. Shorter telomeres have been associated with premature morbidity and an increased risk of age-related diseases. However, this study offered hope that we could reverse aging at a cellular level by re-lengthening telomeres, paving the way for a healthier and longer life.

The Telomere Revelation: A Landmark Study

The study conducted by Dr. Dean Ornish and his team focused on men with low-grade prostate cancer. These individuals adopted diet and lifestyle changes to manage their condition, and the results were astounding. Their immune system cells experienced a significant 10% lengthening of telomeres. This remarkable finding indicated that lifestyle modifications could potentially reverse the aging process at a cellular level—a notion that was once considered beyond our reach.

Dr. Ornish’s Key Points

During a follow-up interview, Dr. Dean Ornish highlighted some essential elements to consider while incorporating lifestyle changes:

    1. Fun, Freedom, Pleasure, and Love: Dr. Ornish emphasized that lifestyle changes should incorporate these elements. When individuals find joy and fulfilment, they are more likely to adopt sustainable changes that enhance overall well-being.
    2. Dietary Plan: Dr. Ornish’s successful dietary plan includes several key components:   – Emphasis on Plant-Based Foods: The diet centres around primarily plant-based foods, such as fruits, vegetables, whole grains, legumes, and soy products. These natural foods eliminate harmful fats and refined sugars and contain essential nutrients that reduce the risk of cancer and other diseases.
      • Whole Foods: The diet encourages the consumption of foods in their natural form, preserving their beneficial fiber content.
      • Reducing Unhealthy Fats: The plan advises reducing the intake of hydrogenated, saturated, and trans fats. Emerging research even suggests that saturated fats may shorten telomeres.
      • Minimizing Sugar and Refined Carbohydrates: High sugar and refined carbohydrate consumption should be limited as they can negatively impact telomere length and overall health.
      • Omega-3 Fatty Acids: Dr. Ornish recommends a daily intake of 4 grams of fish oil or an equivalent supplement. Omega-3 fats like EPA and DHA found in fish oil provide significant health benefits, and even 500 mg per day of EPA/DHA has proven to be beneficial.

Dr. Ornish’s message is clear: Eat well, stress less, move more, and love more. By adhering to these four principles, individuals can manage chronic disease risks, influence aging, and reduce healthcare costs. Promoting such changes, lifestyle medicine has gained significant momentum and offers a promising approach to enhancing overall well-being.

Conclusion

The groundbreaking Lancet study from 2013 opened the door to a new understanding of cellular aging and the potential for its reversal through lifestyle changes. Dr. Dean Ornish’s research has shown that incorporating fun, freedom, pleasure, and love into lifestyle modifications is essential for sustainable change. His dietary plan, emphasizing plant-based foods, whole foods, and healthy fats, offers a practical guide to cellular rejuvenation. The Meschino Wellness Platform supports this approach, facilitating healthy living and promoting well-being.

By adopting these lifestyle changes, individuals can pave the way for a healthier and more fulfilling life, enjoying the benefits of increased telomere length, reduced disease risk, and improved overall health.

References:

  1. Ornish, D., Lin, J., Chan, J. M., Epel, E., Kemp, C., Weidner, G., … & Blackburn, E. H. (2013). Effect of comprehensive lifestyle changes on telomerase activity and telomere length in men with biopsy-proven low-risk prostate cancer: 5-year follow-up of a descriptive pilot study. The Lancet Oncology, 14(11), 1112-1120.

  2. NutraIngredients-USA. (2013, December 13). Lifestyle medicine is the right idea at the right time: Dean Ornish, MD. http://www.nutraingredients-usa.com/Research/Lifestyle-medicine-is-the-right-idea-at-the-right-time-Dean-Ornish-MD.

Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

Adeeva Supplements
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LMU 16 – LDL-Cholesterol: A Key Player in Heart Disease Prevention

LMU-16

LMU 16 – LDL-Cholesterol: A Key Player in Heart Disease Prevention

Source: Medscape Article: July 14, 2016

Lifestyle Medicine Update (July 21, 2016)

Introduction:

This article explores the critical role of LDL-cholesterol (low-density lipoprotein) in heart disease and cardiovascular risk. Elevated levels of LDL-cholesterol have long been associated with an increased risk of heart disease and related deaths. This harmful cholesterol accumulates in artery walls, leading to atherosclerosis and narrowing of blood vessels, which can result in life-threatening events such as heart attacks and strokes. Understanding the significance of LDL-cholesterol and its impact on heart health is essential for preventing cardiovascular diseases, which continue to be a leading cause of death in our society.

The Importance of LDL-Cholesterol Levels

Dr. Catapano, President of the European Atherosclerosis Study, emphasizes that a high level of LDL-cholesterol is a primary culprit in heart and cardiovascular diseases. Research indicates that the safest value for LDL-cholesterol is below 70 mg/dl (in the American unit) or 1.8 mmol/L (in the Canadian team). Keeping LDL cholesterol levels within this range is crucial for minimizing the risk of developing atherosclerosis and its associated complications.

Lifestyle Modifications for Lowering LDL-Cholesterol

For individuals with elevated LDL-cholesterol levels who have not experienced a heart attack, lifestyle changes are recommended as the first line of defence. These modifications can be effective, even for those already on cholesterol-lowering medications. Some proven lifestyle changes to lower LDL-cholesterol include:

  1. Reducing Intake of Beef and Pork Products: Choosing leaner protein sources can help reduce the intake of saturated fats.
  2. Avoiding High-Fat Dairy Products: opt for low-fat or non-fat dairy alternatives to reduce saturated fat consumption.
  3. Eliminating Trans Fats: Avoiding deep-fried and processed foods can significantly reduce trans-fat intake.
  4. Consuming Cholesterol-Lowering Foods: Foods like beans, peas, artichokes, and soy can help lower cholesterol levels.
  5. Adding Fiber Supplements: Psyllium husk fiber, ground flaxseed, and oat fiber can contribute to lowering cholesterol levels.
  6. Regular Endurance Exercises and Healthy Weight Maintenance: Regular physical activity and maintaining a healthy weight can positively influence cholesterol levels.


Understanding the Full Picture of Heart Disease Risk

While LDL-cholesterol significantly contributes to heart disease, other factors such as age, gender, smoking, family history, total cholesterol, HDL-cholesterol, triglyceride levels, and homocysteine levels also impact cardiovascular risk. A comprehensive approach to heart health involves considering these factors with LDL-cholesterol levels.

Sudden Cardiac Death and Heart Disease Risk

Sudden cardiac death is often the first sign of cardiovascular disease and can occur without warning. Recent findings from the Framingham Heart Study in 2016 revealed that men are more than twice as likely to die from sudden cardiac death than women. Men aged 45-70 face approximately a 10% increased risk, while women have a 3-3.5% risk. Individuals with additional cardiovascular risk factors, such as high LDL cholesterol and high blood pressure, are at an even higher risk.

Taking Control of Heart Health

Understanding one’s cholesterol and blood pressure numbers and using diet and lifestyle to optimize these values throughout life is essential for heart health. Consistent effort and vigilance are necessary to reduce the risk of heart disease and its potential consequences.

Conclusion

LDL-cholesterol plays a crucial role in heart disease prevention, and maintaining levels below 70 mg/dl or 1.8 mmol/L is essential for reducing cardiovascular risk. Embracing lifestyle modifications and adopting a heart-healthy diet can significantly impact cholesterol levels, helping to prevent atherosclerosis and related complications. Regular monitoring of heart health and consulting with healthcare professionals can further enhance preventive measures against heart disease.

References:

Dr. Catapano’s Medscape Interview: 

[Link: http://www.medscape.com/viewarticle/866069nlid=108316_1842&src=WNL_mdplsfeat_160719_mscpedit_wir&uac=62 15BJ&spon=17&impID=1159644&faf=1#vp_2]
Sudden Cardiac Death Stats from Framingham Study, Update 2016: [Link: http://www.medscape.com/viewarticle/865714]


Eat Smart, Live Well, Look Great,

Dr. Meschino

Introduction:

This article explores the critical role of LDL-cholesterol (low-density lipoprotein) in heart disease and cardiovascular risk. Elevated levels of LDL-cholesterol have long been associated with an increased risk of heart disease and related deaths. This harmful cholesterol accumulates in artery walls, leading to atherosclerosis and narrowing of blood vessels, which can result in life-threatening events such as heart attacks and strokes. Understanding the significance of LDL-cholesterol and its impact on heart health is essential for preventing cardiovascular diseases, which continue to be a leading cause of death in our society.

The Importance of LDL-Cholesterol Levels

Dr. Catapano, President of the European Atherosclerosis Study, emphasizes that a high level of LDL-cholesterol is a primary culprit in heart and cardiovascular diseases. Research indicates that the safest value for LDL-cholesterol is below 70 mg/dl (in the American unit) or 1.8 mmol/L (in the Canadian team). Keeping LDL cholesterol levels within this range is crucial for minimizing the risk of developing atherosclerosis and its associated complications.

Lifestyle Modifications for Lowering LDL-Cholesterol

For individuals with elevated LDL-cholesterol levels who have not experienced a heart attack, lifestyle changes are recommended as the first line of defence. These modifications can be effective, even for those already on cholesterol-lowering medications. Some proven lifestyle changes to lower LDL-cholesterol include:

  1. Reducing Intake of Beef and Pork Products: Choosing leaner protein sources can help reduce the intake of saturated fats.
  2. Avoiding High-Fat Dairy Products: opt for low-fat or non-fat dairy alternatives to reduce saturated fat consumption.
  3. Eliminating Trans Fats: Avoiding deep-fried and processed foods can significantly reduce trans-fat intake.
  4. Consuming Cholesterol-Lowering Foods: Foods like beans, peas, artichokes, and soy can help lower cholesterol levels.
  5. Adding Fiber Supplements: Psyllium husk fiber, ground flaxseed, and oat fiber can contribute to lowering cholesterol levels.
  6. Regular Endurance Exercises and Healthy Weight Maintenance: Regular physical activity and maintaining a healthy weight can positively influence cholesterol levels.

Understanding the Full Picture of Heart Disease Risk

While LDL-cholesterol significantly contributes to heart disease, other factors such as age, gender, smoking, family history, total cholesterol, HDL-cholesterol, triglyceride levels, and homocysteine levels also impact cardiovascular risk. A comprehensive approach to heart health involves considering these factors with LDL-cholesterol levels.

Sudden Cardiac Death and Heart Disease Risk

Sudden cardiac death is often the first sign of cardiovascular disease and can occur without warning. Recent findings from the Framingham Heart Study in 2016 revealed that men are more than twice as likely to die from sudden cardiac death than women. Men aged 45-70 face approximately a 10% increased risk, while women have a 3-3.5% risk. Individuals with additional cardiovascular risk factors, such as high LDL cholesterol and high blood pressure, are at an even higher risk.

Taking Control of Heart Health

Understanding one’s cholesterol and blood pressure numbers and using diet and lifestyle to optimize these values throughout life is essential for heart health. Consistent effort and vigilance are necessary to reduce the risk of heart disease and its potential consequences.

Conclusion

LDL-cholesterol plays a crucial role in heart disease prevention, and maintaining levels below 70 mg/dl or 1.8 mmol/L is essential for reducing cardiovascular risk. Embracing lifestyle modifications and adopting a heart-healthy diet can significantly impact cholesterol levels, helping to prevent atherosclerosis and related complications. Regular monitoring of heart health and consulting with healthcare professionals can further enhance preventive measures against heart disease.

References:

  1. Dr. Catapano’s Medscape Interview: [Link:                                                                                      http://www.medscape.com/viewarticle/866069nlid=108316_1842&src=WNL_mdplsfeat_160719_mscpedit_wir&uac=62 15BJ&spon=17&impID=1159644&faf=1#vp_2]
  2. Sudden Cardiac Death Stats from Framingham Study, Update 2016: [Link:                                                                                                    http://www.medscape.com/viewarticle/865714] 
Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

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LMU 15 – Green Tea Catechins: A Promising Strategy for Preventing and Managing Prostate Cancer

LMU-15

LMU 15 – Green Tea Catechins: A Promising Strategy for Preventing and Managing Prostate Cancer

Source: Journal Cancer Research, 2006, and Journal Cancer Prevention and Research, 2009

Lifestyle Medicine Update (July 16, 2016)

Introduction:

Green tea has gained widespread recognition for its numerous health benefits, and recent scientific investigations have highlighted the potential role of green tea catechins (GTCs) in the prevention and management of prostate cancer. Groundbreaking studies have revealed that GTCs can stabilize and even reverse precancerous prostate lesions, known as high-grade intra-epithelial neoplasia (HGPIN), which often precede the development of prostate cancer.

Study 1: Preventing Prostate Cancer Progression

In 2006, a significant study published in the Journal of Cancer Research focused on 60 men diagnosed with HGPIN. These men were followed for a year, with half receiving a daily supplement of GTCs containing 600 mg (three capsules of 200 mg each), while the other half receiving a placebo. The results were remarkable, as only 3% of the men in the GTCs-treated group developed tumors, compared to a significantly higher incidence of 30% among the placebo group. Moreover, the GTCs-treated group exhibited consistently lower levels of prostate-specific antigen (PSA) and improvements in symptoms related to benign prostatic hyperplasia and lower urinary tract issues.

Study 2: Impact on Established Prostate Cancer

In 2009, a follow-up study published in the Journal of Cancer Prevention Research looked at the effects of GTCs in men with localized prostate cancer who were awaiting surgical treatment (radical prostatectomy). Twenty-six men with positive prostate biopsies were given a daily supplement containing 800 mg of GTCs until the day of surgery. The results showed a decrease in various prostate cancer biomarkers, including PSA, hepatocyte growth factor (HGF), vascular endothelial growth factor (VEGF), insulin-like growth factor (IGF-I), and its binding proteins (IGFBP-3).

Mechanism of Action

The proposed mechanism of action for GTCs in prostate cancer involves inhibiting the HGF/c-Met signalling pathway, which plays a crucial role in cancer progression and metastasis. C-Met receptors are often over-expressed in prostate tumors, and high levels of HGF are associated with metastatic disease and reduced survival rates. GTCs have demonstrated the ability to block the production of HGF and VEGF in prostate cancer-associated fibroblast cell lines, providing further evidence of their potential in managing prostate cancer.

The Promise of Green Tea Catechins as Adjuvant Therapy

Based on these compelling findings, green tea catechins show great promise as adjuvant therapy in men with prostate cancer. The data suggest that GTCs may contribute to lowering cytokine levels, such as HGF and VEGF, which are known to drive prostate cancer progression. For those interested in supporting prostate health, consuming 3-5 cups of green tea daily or supplementing with green tea catechins (approximately 200-600 mg daily) could benefit their routine.

Conclusion: Embracing Green Tea Catechins for Prostate Health

The research on green tea catechins and their impact on prostate health continues to provide encouraging results. Incorporating green tea into daily habits or considering GTCs supplementation could be a valuable step toward maintaining prostate health and reducing the risk of prostate cancer.

References:

  1. Bettuzzi S., Brausi M., Rizzi F., et al. Chemoprevention of Human Prostate Cancer by Oral Administration of Green Tea Catechins in Volunteers with High-Grade Prostate Intraepithelial Neoplasia: A Preliminary Report from a One-Year Proof-of-Principle Study. Cancer Res., January 15, 2006, 66; 123.
  2. McLarty J., Bigelow R., Smith M., et al. Tea Polyphenols Decrease Serum Levels of Prostate-Specific Antigen, Hepatocyte Growth Factor, and Vascular Endothelial Growth Factor in Prostate Cancer Patients and Inhibit the Production of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor In vitro. Cancer Prev. Res. July 2009, 2; 673.
Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

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LMU 14 – Green Tea Catechins: A Path to Improved Health

LMU-14

LMU 14 – Green Tea Catechins: A Path to Improved Health

Source:

Lifestyle Medicine Update (July 9, 2016)

Introduction:

Green tea has a long-standing reputation for its health benefits, and ongoing research continues to unveil its potential advantages. In this article, we explore the impact of green tea catechins on various health markers and delve into their potential to promote improved health and well-being.

The Study: Unravelling the Power of Green Tea Catechins

In a groundbreaking study published in the Journal of Nutrition Research in June 2012, researchers set out to investigate the effects of green tea catechins on individuals with obesity-related hypertension. Catechins are potent medicinal compounds found abundantly in green tea, surpassing the levels found in black tea. Previous evidence has suggested that these catechins could aid fat burning, regulate blood pressure and blood sugar, lower cholesterol levels, and reduce inflammation.

The Participants

The study involved 56 obese and hypertensive men and women closely monitored over three months. Half of the participants received a daily supplement containing 379 mg of green tea extract (high in catechins), while the other half received a placebo.

The Remarkable Results

The results demonstrated significant benefits for the group taking the green tea extract supplement:

  1. Reduction in High Blood Pressure: Hypertension is a significant risk factor for cardiovascular diseases, and the study found that green tea catechins positively lowered blood pressure levels.
  2. Improvement in Insulin Function and Blood Sugar Regulation: Maintaining stable blood sugar levels is crucial for individuals with obesity and diabetes. The study showed that green tea catechins played a role in enhancing insulin sensitivity and regulating blood sugar.
  3. Decline in Bad Cholesterol (LDL-Cholesterol): High levels of LDL-cholesterol are linked to an increased risk of heart disease. The study revealed that green tea catechins helped reduce LDL-cholesterol levels.
  4. Increase in Good Cholesterol (HDL-Cholesterol): HDL-cholesterol, often called “good” cholesterol, is protective against heart disease. The study demonstrated that green tea catechins contributed to an elevation in HDL-cholesterol levels.

  5. Reduction in Inflammation: Chronic inflammation is associated with numerous health problems, including heart disease and certain cancers. The study showed that green tea catechins had an anti-inflammatory effect, as evidenced by decreased blood CRP levels (C-reactive protein).

Conclusive Findings

The researchers concluded that daily supplementation of green tea extract favorably influenced blood pressure, insulin resistance, inflammation, oxidative stress, and lipid profile in individuals with obesity-related hypertension.

Exploring Beyond: Green Tea Catechins and Cancer Prevention

Beyond cardiovascular benefits, additional studies have highlighted the potential of green tea catechins in preventing the progression of precancerous cells in the prostate gland and improving markers related to tumor growth and metastasis in prostate and breast cancer patients.

Recommended Daily Intake

For general health benefits, consuming at least 150 mg of green tea catechins per day is recommended. One cup of steeped green tea typically contains between 50-70 mg of catechins, with some brands, like Lipton’s Green Tea, offering 71 mg per cup. Therefore, consuming 2-3 cups of green tea daily is wise.

Supplementation for Specific Health Conditions

If you are overweight, have type 2 diabetes, or have high cholesterol, consider supplementing your green tea intake with 200-300 mg of green tea extract standardized to 50% catechin content or ECGC. Studies have shown that catechins from supplements are better absorbed than those obtained from steeped green tea.

Embrace the Green Tea Benefits

Regardless of how you consume it, green tea and its catechin content offer impressive health attributes that can contribute to your overall well-being. By incorporating green tea into your daily routine, you can embark on a path to improved health and a healthier lifestyle.

Conclusion

The 2012 study paved the way for understanding the exceptional health benefits of green tea catechins, ranging from cardiovascular improvements to anti-inflammatory effects. Subsequent research has continued to explore green tea’s potential to mitigate the risk of certain cancers. As scientific exploration continues, green tea and its catechins will likely unveil even more health-promoting properties. Embracing this ancient beverage as part of a healthy lifestyle may be a simple yet effective way to pave the path to improved health and well-being. So, why not raise a cup of green tea today and savor its goodness?

Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

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LMU 13 – The Health Benefits of Ground Flaxseed: A Rich Source of Lignans and Omega-3 Fats

LMU-13

LMU 13 – The Health Benefits of Ground Flaxseed: A Rich Source of Lignans and Omega-3 Fats

Source: Comprehensive Reviews in Food Science and Food Safety, 2010

Lifestyle Medicine Update (June 29, 2016)

Introduction:

Ground flaxseed is a unique and powerful food packed with beneficial compounds that can positively impact human health. Its key components are alpha-linolenic acid, an essential omega-3 fatty acid, and SLD (secoisolariciresinol diglycoside), a unique lignan. In this article, we will explore the health benefits of ground flaxseed, with a particular focus on its role in cancer prevention, hormone regulation, and overall well-being.

The Power of Lignans: Enterolactone and Enterodiol

Ground flaxseed’s exceptional lignan content is a standout feature. Flaxseed contains an abundance of lignans that are metabolized into Enterolactone and Enterodiol by gut bacteria. These compounds, classified as phytoestrogens, have shown promising anti-cancer effects, particularly in breast and prostate cancer.

Cancer Prevention: Fighting Breast and Prostate Cancer

Studies have revealed that Enterolactone and Enterodiol can reduce the form of estrogen (16-hydroxy estrone) that is considered carcinogenic while simultaneously increasing the shape that minimizes the risk of breast and endometrial cancer (2-hydroxy estrone). Ground flaxseed’s potential in managing PMS symptoms, fibrocystic breast disease, uterine fibroids, and possibly endometriosis is beneficial for premenopausal women with high estrogen levels. For menopausal women with low estrogen levels, ground flaxseed supplementation may help alleviate menopausal symptoms through mild estrogen stimulation in target tissues.

Prostate Health and Cancer Risk Reduction

Ground flaxseed has demonstrated promise in inhibiting cell division rates in prostate cancer cells and slowing tumor growth in men with localized prostate cancer. The combination of ground flaxseed with a low-fat diet has been associated with reduced PSA (prostate-specific antigen) levels, suggesting a potentially lower risk of prostate cancer.

Beyond Breast and Prostate: Other Cancers

Experimental studies have also shown that flaxseed can inhibit colon and skin cancers in cell cultures and animal models. Its antioxidant effects and ability to prevent chromosomal DNA damage further highlight its potential in cancer prevention.

The Role of Fiber in Ground Flaxseed

Ground flaxseed is rich in lignans and omega-3 fats and contains both types of dietary fiber—cholesterol-lowering fiber and fiber that improves intestinal regularity. These fibers contribute to lower blood sugar levels and improved insulin sensitivity, making ground flaxseed beneficial for individuals with diabetes.

Unlocking the Medicinal Properties: Ground vs. Whole Flaxseed

To fully access the medicinal properties of flaxseed, it is crucial to consume it in ground form. The outer husk of flaxseeds is too harsh for digestive enzymes to break down, hindering access to the essential ingredients. We recommend a daily intake of 1 to 2 tablespoons of ground flaxseed as part of a wellness program.

Other Sources of Cancer-Fighting Lignans

While ground flaxseed contains many lignans, other plant foods also provide cancer-fighting lignans. Grains such as wheat, barley, oats, legumes like beans, lentils, and soybeans, and vegetables such as garlic, asparagus, broccoli, and carrots contribute to a well-rounded diet that supports overall health.

Conclusion

Ground flaxseed is a nutritional powerhouse, offering essential omega-3 fats, lignans, and dietary fiber, contributing to numerous health benefits. Various studies have well-documented its potential in cancer prevention, hormone regulation, and overall well-being. Individuals can optimize their health and well-being by incorporating ground flaxseed into a balanced diet.

Reference:

Gustavo A. González-Sarrías, Navindra P. Seeram. Flaxseed Lignans: Source, Biosynthesis, Metabolism, Antioxidant Activity, Bio-Active Components, and Health Benefits. Comprehensive Reviews in Food Science and Food Safety. Vol 9, 2010:261-269. [Link: http://onlinelibrary.wiley.com/doi/10.1111/j.1541-4337.2009.00105.x/abstract]

Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

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LMU 12 – Understanding the Gluten-Free Movement: Celiac Disease, Wheat Allergy, and Gluten Sensitivity

LMU-12

LMU 12 – Understanding the Gluten-Free Movement: Celiac Disease, Wheat Allergy, and Gluten Sensitivity

Source: Journal of Clinical Nutrition, April, 2015 (Vol. 34, Issue 2, pages: 189-194)

Lifestyle Medicine Update (June, 16, 2016)

Introduction:

Gluten has become a hot topic due to the rising popularity of the gluten-free movement. It combines two proteins in wheat and other grains: gliadin and glutenin.

Celiac Disease: The Autoimmune Disorder

Among these proteins, gliadin is responsible for causing problems in individuals with Celiac Disease. Celiac Disease is an autoimmune disorder triggered by the gliadin fraction of gluten, leading to an abnormal immune response in the small intestine. This results in an inflammatory reaction that damages the gut lining and interferes with nutrient absorption. Common manifestations of Celiac Disease include chronic diarrhea, abdominal distension after meals, weight loss, growth failure in children, and anemia. Testing for Celiac Disease involves a simple blood test and confirmation through an intestinal biopsy.

Managing Celiac Disease: Avoiding Gluten

The primary management of Celiac Disease involves avoiding all food sources of gluten, which include wheat, barley, bulgur, oats (due to potential contamination), rye, seitan, triticale, and mir. Gluten may also be present in ingredients like barley malt, chicken broth, malt vinegar, some salad dressings, veggie burgers (if not specified gluten-free), and soy sauce, as well as common seasonings and spice mixes.

Wheat Allergy: An Allergic Reaction

Approximately 1% of the population has Celiac Disease, and an additional 1% has a wheat allergy. Wheat allergy involves an allergic reaction to wheat proteins, including gluten, and often presents with atopic symptoms like hay fever, hives, eczema, and asthma.

Gluten Sensitivity or Intolerance: A New Health Condition

In 2012, researchers recognized and published a new health condition called Gluten Sensitivity or Intolerance. This condition shares symptoms with Celiac Disease but does not show the presence of antibodies or celiac damage in the intestinal tract. About 6% of the population is estimated to have gluten sensitivity, and avoiding gluten-containing foods has been shown to improve intestinal symptoms such as bloating, frequent diarrhea, cramping pain, and associated joint pain and fatigue. Gluten Sensitivity is also common in people with irritable bowel syndrome (IBS), and avoiding gluten in such cases can help reduce IBS symptoms. However, not all cases of IBS are linked to gluten sensitivity.

Gluten’s Impact on Schizophrenia and Autism Spectrum Disorder

Evidence suggests that gluten sensitivity might trigger symptoms in some patients with schizophrenia or autism spectrum disorder. Though only a tiny percentage of patients may benefit, it is worth considering a simple trial of avoiding gluten to enhance the treatment of schizophrenia and improve the symptoms of autism.

The Wider Perspective: Gluten Issues in the Population

It is essential to note that Celiac Disease, wheat allergy, and gluten sensitivity combined account for less than 10% of the entire population. For most people, gluten is not a problem. Therefore, going gluten-free is only necessary if an apparent problem or a medical diagnosis requires it.

Gluten-Free Diets: A Cautionary Note

For individuals interested in gluten-free diets, it is crucial to understand that gluten-free foods often contain added fats and carbohydrates to replace gluten. For those without gluten sensitivity or Celiac Disease, these additional calories may not be beneficial and can lead to other health concerns.

Conclusion

In conclusion, while the gluten-free movement has gained significant attention, it is primarily essential for individuals with Celiac Disease, wheat allergy, or gluten sensitivity. For everyone else, gluten is generally not a problem. If you experience the abdominal symptoms mentioned earlier, and your doctor cannot identify a specific cause, you may consider exploring gluten sensitivity. It is always advisable to consult with healthcare professionals or registered dietitians before making significant dietary changes.

References:

  1. Clinical Nutrition, April 2015. http://www.clinicalnutritionjournal.com/article/S0261-5614(14)00218-0/fulltext
  2. Gluten-free Foods: http://www.healthline.com/health/allergies/gluten-food-list#Overview1
  3. Other Gluten Reference and Resource: http://www.livescience.com/53265-what-is-gluten.html

  4. Wheat Allergy Information: http://acaai.org/allergies/types/food-allergies/types-food-allergy/wheat-gluten-allergy

Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

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